Results 181 to 190 of about 234,397 (278)

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

POSS Polyimide Composite Sealed Triple‐Junction GaAs Thin‐Film Solar Cell for Long‐Term Low Earth Orbit Serve

open access: yesAdvanced Science, EarlyView.
Ultrathin oxide layer and ultraviolet absorbent are introduced into polyhedral oligomeric silsesquioxane (POSS) polyimide to improve the transmittance conservation and realize near zero mass loss against ultraviolet and atomic oxygen exposures. The POSS polyimide composite sealed triple‐junction GaAs thin‐film solar cell exhibits enhanced endurance of ...
Min Qian   +3 more
wiley   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Phase and Valence State Engineering of MOFs-Derived Iron Oxide@Carbon Polyhedrons for Advanced Microwave Absorption. [PDF]

open access: yesNanomaterials (Basel)
Yang X   +9 more
europepmc   +1 more source

Multi‐Soliton Microcombs Enable Ultrafast Nanometric‐Precision Ranging and Photon‐Level Detection

open access: yesAdvanced Science, EarlyView.
Our work first demonstrates dual‐multi‐soliton ranging and confirms its multifunctional capability. The method achieves ultrafast and nanometric‐precision measurement. For practical applications, we further extend the multi‐soliton states to photon‐level ranging.
Jiawen Zhi   +10 more
wiley   +1 more source

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng   +10 more
wiley   +1 more source

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