Results 81 to 90 of about 5,074,442 (338)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Use of Microwave Radiometry to Monitor Thermal Denaturation of Albumin

Frontiers in Physiology, 2018
This study monitored thermal denaturation of albumin using microwave radiometry. Brightness Temperature, derived from Microwave Emission (BTME) of an aqueous solution of bovine serum albumin (0.1 mM) was monitored in the microwave frequency range 3.8–4.2
Yuri Ivanov, Andrey F. Kozlov, Rafael A. Galiullin, Vadim Y. Tatur, Vadim S. Ziborov, Nina D. Ivanova, Tatyana O. Pleshakova, Sergey G. Vesnin, Sergey G. Vesnin, Igor Goryanin, Igor Goryanin, Igor Goryanin   +11 more
doaj   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

Use of Radiative Transfer Model for Inter-Satellite Microwave Radiometer Calibration

Remote Sensing
This paper describes the benefits of using a microwave radiative transfer model (RTM) to improve the inter-satellite radiometric calibration (XCAL) between two independent satellite microwave radiometers.
Patrick N. De La Llana, Faisal Bin Kashem, W. Linwood Jones   +2 more
doaj   +1 more source

Seawinds Radiometer Brightness Temperature Calibration And Validation [PDF]

, 2005
The NASA SeaWinds scatterometer is a radar remote sensor which operates on two satellites; NASA\u27s QuikSCAT launched in June 1999 and on Japan\u27s ADEOS-II satellite launched in December 2002.
Rastogi, Mayank
core  

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Topography Effects on Microwave Emission Transmission of Snowpack and Snow Depth Retrieval

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Advancements in snow depth retrieval from passive microwave remote sensing data have mainly focused on influence of varying snow characteristics and forests, while neglecting the complicated mountainous terrain.
L. Dai, T. Che, Z. Hu
doaj   +1 more source

Incorporation of Passive Microwave Brightness Temperatures in the ECMWF Soil Moisture Analysis [PDF]

Remote Sensing, 2015
For more than a decade, the European Centre for Medium-Range Weather Forecasts (ECMWF) has used in-situ observations of 2 m temperature and 2 m relative humidity to operationally constrain the temporal evolution of model soil moisture. These observations are not available everywhere and they are indirectly linked to the state of the surface, so under ...
openaire   +3 more sources

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source