Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang +14 more
wiley +1 more source
Energy-Efficient Microwave Heating: Governing Role of the Thermal Profile in Heating Liquid. [PDF]
Jia S, Huang K, Wang S, Wang H.
europepmc +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Mechanisms of 915 MHz Microwave Thermal Treatment on Physicochemical Properties and Microbial Communities in Sugarcane Continuous Cropping Soil. [PDF]
Mao J +7 more
europepmc +1 more source
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
Imaging cell phone radiation in tissue mimics with hyperpolarized low-field MRI. [PDF]
Ogier SE +11 more
europepmc +1 more source
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok +13 more
wiley +1 more source
Gradient multilayered RTV silicone rubber composites with carbonyl iron, conductive carbon, and ZnS for broadband microwave absorption and infrared stealth. [PDF]
Hao L +7 more
europepmc +1 more source
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath +9 more
wiley +1 more source
Let There Be Light: Photo-Induced Reaction Synthesis-Advancing Manufacturing Horizons. [PDF]
Brachtl S, Rodriguez R, Fujimoto K.
europepmc +1 more source

