Results 71 to 80 of about 28,063 (287)

Investigating privacy in an ambient world [PDF]

open access: yes, 2006
Ambient Intelligence (AmI) and ubiquitous computing allow us to consider a future where computation is embedded into our daily social lives. This vision raises its own important questions and augments the need to understand how people will achieve and ...
Briggs, Pamela, Little, Linda
core  

Predictors of poor glycaemic control in older persons with type 2 diabetes mellitus [PDF]

open access: yes, 2015
INTRODUCTION: We assessed the predictors of poor glycaemic control among older patients with type 2 diabetes mellitus (T2DM) in Malaysia. METHODS: This cross-sectional study used the data of 21,336 patients aged ≥ 60 years with T2DM from the Adult ...
Bujang, Mohamad Adam   +7 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Soft computing and its use in risk management [PDF]

open access: yes, 2007
New analytical methods have begun to be used in risk management. The methods such as fuzzy logic, neural network and genetic algorithms rank among them.
Dostál, Petr
core  

Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations [PDF]

open access: yes, 2018
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access.
Ernest, Terry B.   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Age-dependent female responses to a male ejaculate signal alter demographic opportunities for selection [PDF]

open access: yes, 2013
A central tenet of evolutionary explanations for ageing is that the strength of selection wanes with age. However, data on age-specific expression and benefits of sexually selected traits are lacking—particularly for traits subject to sexual conflict. We
Chapman, T.   +3 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Impact of modifiable healthy lifestyle adoption on lifetime gain from middle to older age [PDF]

open access: hybrid, 2022
Ryoto Sakaniwa   +6 more
openalex   +1 more source

Older Adults’ Social Relations: Life Satisfaction to Widowhood [PDF]

open access: yes, 2018
The objective of this study was to examine the breadth and depth of relationships with relatives and friends and the possible implications of those relationships with regards to life satisfaction to widowhood.
Ahn, Bonnie, Kang, Hyunsook
core   +1 more source

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