Results 161 to 170 of about 9,251,562 (304)

Burden of Middle-Aged and Elderly Patients With Non-Hodgkin Lymphoma From 1990 to 2021: A Systematic Analysis Based on the Global Burden of Disease 2021. [PDF]

Cancer Med
Chen Y, Jiang Y, Xu Y, Ma Y, Yao W, Cao Q, Zhang X, Peng L, Tang Y, Cheng Y, Ren R, Chen X, Lang H.   +12 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Clinical characteristics of ground-glass opacities in young patients : a single-center retrospective study. [PDF]

J Cardiothorac Surg
Song X, Hu P, Fu X, Fu S.
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Redescription of <i>Ehlersileanira vulturis</i> (Horst, 1917) n. comb. reinst. and description of two new species of <i>Ehlersileanira</i> (Annelida, Sigalionidae) from Indonesia and the Philippines. [PDF]

PeerJ
Cruz-Gómez C, Chuar CH.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Middle Country Central School District and Middle Country Association of Teacher Aides (2013) [PDF]

, 2013

core   +1 more source

Gestational age amplifies the risk of airflow obstruction in adult smokers with asthma. [PDF]

ERJ Open Res
Konradsen JR, Stridsman C, Andersson N, Backman H, Vanfleteren LEGW, Ödling M.   +5 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Middle County Central School District and Middle County Secretarial Association, Clerical Unit (2006) [PDF]

, 2006

core   +1 more source