Results 91 to 100 of about 2,578,592 (359)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Normative data for middle-aged Brazilians in the Mattis Dementia Rating Scale

open access: yesDementia & Neuropsychologia, 2020
. Despite the advances in the diagnosis of dementia, neuropsychological assessment remains an important tool. The Mattis Dementia Rating Scale (DRS) was designed to evaluate people with suspected dementia and allows for the analysis of different ...
Guilherme Almeida Carvalho   +1 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Meaning of Happiness Based on ERG Theory in Middle-Aged Korean Women [PDF]

open access: yesKorean Journal of Women Health Nursing, 2019
PURPOSE: The purpose of this study was to explore the components and nature of happiness in middle-aged women in Korea. METHODS: Thirty middle-aged women living in metropolitan Seoul and Gyeonggi and Chungcheong provinces agreed to participate in this ...
Hee Jin Shin, Jeung Im Kim
doaj   +1 more source

X-ray Emission from Middle-Aged Gamma-Ray Pulsars [PDF]

open access: yesarXiv, 2015
Electrons/positrons produced in a pulsar magnetosphere emit synchrotron radiation, which is widely believed as the origin of the non-thermal X-ray emission detected from pulsars. Particles are produced by curvature photons emitted from accelerated particles in the magnetosphere. These curvature photons are detected as pulsed $\gamma$-ray emissions from
arxiv  

Two-Step Acceleration Model of Cosmic Rays at Middle-Aged SNR

open access: yes, 2010
Recent gamma-ray observations of middle-aged supernova remnants revealed a mysterious broken power-law spectrum. Using three-dimensional magnetohydrodynamics simulations, we show that the interaction between a supernova blast wave and interstellar clouds
Abdo   +23 more
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Development and Validation of the Happiness Scale for Middle-Aged Women Based on Existence, Relation, and Growth Theory

open access: yesAsian Nursing Research, 2021
Purpose: This study aimed at developing a happiness assessment scale for middle-aged women (HAS-MW) in Korea. Methods: Preliminary items for the scale were drafted from the results of literature review and personal interviews and open-ended questions ...
Hee-Jin Shin, Jeung-Im Kim
doaj  

Element Stratification in the Middle-Aged Type Ia Supernova Remnant G344.7-0.1

open access: yes, 2020
Despite their importance, a detailed understanding of Type Ia supernovae (SNe Ia) remains elusive. X-ray measurements of the element distributions in supernova remnants (SNRs) offer important clues for understanding the explosion and nucleosynthesis ...
Fukushima, Kotaro   +9 more
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

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