Results 121 to 130 of about 12,195,030 (401)

The influence of middle-aged and older adults’ social capital and education on physical function: evidence from the China Health and Retirement Longitudinal Study

open access: yesFrontiers in Public Health
BackgroundPopulation aging is a major global trend with significant social, economic, and health implications. In China, the increasing aging population presents challenges, including increased chronic diseases and disabilities.
Tingfai Man   +8 more
doaj   +1 more source

Influence of Body Composition on Arterial Stiffness in Middle-Aged Adults: Healthy UAL Cross-Sectional Study [PDF]

open access: yes, 2019
Background and objectives: Several anthropometric and body composition parameters have been linked to arterial stiffness (AS) as a biomarker of cardiovascular disease. However, little is known about which of these closely related factors is more strongly
Alcaraz Ibáñez, Manuel   +4 more
core   +1 more source

Variability in heart rate recovery measurements over 1 year in healthy, middle-aged adults. [PDF]

open access: yes, 2014
This study assessed the longer-term (12-month) variability in post-exercise heart rate recovery following a submaximal exercise test. Longitudinal data was analysed for 97 healthy middle-aged adults (74 male, 23 female) from 2 occasions, 12 months apart.
Carroll, S, Ingle, L, Mellis, MG
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Regional abdominal adiposity is associated with BMI‐related brain regions in middle‐aged adults at high risk of Alzheimer’s dementia [PDF]

open access: bronze, 2021
Sapir Golan   +6 more
openalex   +1 more source

A middle-aged man with cellulitis [PDF]

open access: yes, 2016
A middle-aged man presents with an extremely painful swollen red leg and signs of sepsis. He has a history of chronic venous insufficiency, obesity, diabetes, hypertension and obstructive sleep apnoea.
Fulde, G, Sullivan, R
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

HIV/AIDS in people aged 50 and older in the province of Las Tunas, a fifteen year study

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: the prevalence of infection by the human immunodeficiency virus (HIV) is increasing in the population aged over 50 years, both due to increased survival and new diagnoses.Objective: to characterize the people aged 50 years and older ...
Martha Odalis Cabrales-León   +4 more
doaj  

β-Alanine supplementation increased physical performance and improved executive function following endurance exercise in middle aged individuals [PDF]

open access: gold, 2018
Taylor Furst   +5 more
openalex   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

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