Results 151 to 160 of about 12,195,030 (401)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Emotional Symptoms and Health Complaints for Patients Seeking Psychomotor Physiotherapy

open access: yesFysioterapeuten, 2008
Aim: Because patients seeking Norwegian psychomotor physiotherapy (PMF) rarely have been described with validated, psychometrically sound instruments, we used six questionnaires to characterize these patients in terms of subjective health complaints and ...
Monica H. Breitve   +2 more
doaj  

O uso da equoterapia como recurso terapêutico para melhora do equilíbrio estático em indivíduos da terceira idade

open access: yesRevista Brasileira de Geriatria e Gerontologia
Resumo Objetivo : Mensurar a melhora do equilíbrio estático em indivíduos da terceira idade com a prática da equoterapia. Materiais e métodos : estudo experimental, clínico, pré e pós-teste.
Tiago Toigo   +2 more
doaj   +1 more source

The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.

open access: yesJournal of the American Medical Association (JAMA), 2002
H. Lakka   +6 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The Effect of Aquatic Balance Exercise With Weighted Vest on the Balance Recovery Strategy of Middle-Aged Women

open access: yesPhysical Treatments, 2018
Purpose: Disturbances in balance and also regaining the balance strategy is very important in the middle-aged women who are near their menopause and subject to severe hormonal and physiological changes, reduced muscle strength, and decreased bone density.
Niloufar Rahmani   +2 more
doaj  

The Identification of the Challenges and Developmental Tasks of Middle and Old age People: A Hermeneutic Study

open access: green, 2021
Maryam Falahatpishe Baboli   +4 more
openalex   +2 more sources

Older Workers and On-the-Job Training in Canada: Evidence from the WES Data [PDF]

open access: yes
This paper provides evidence of on-the-job training among older workers in Canada. It also examines the effect of age associated with on-the-job training.
G.B. Cooke, I.U. Zeytinoglu, K. Harry
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Home - About - Disclaimer - Privacy