Results 151 to 160 of about 10,494,190 (367)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Development and Validation of the Happiness Scale for Middle-Aged Women Based on Existence, Relation, and Growth Theory

open access: yesAsian Nursing Research, 2021
Purpose: This study aimed at developing a happiness assessment scale for middle-aged women (HAS-MW) in Korea. Methods: Preliminary items for the scale were drafted from the results of literature review and personal interviews and open-ended questions ...
Hee-Jin Shin, Jeung-Im Kim
doaj  

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

O uso da equoterapia como recurso terapêutico para melhora do equilíbrio estático em indivíduos da terceira idade

open access: yesRevista Brasileira de Geriatria e Gerontologia
Resumo Objetivo : Mensurar a melhora do equilíbrio estático em indivíduos da terceira idade com a prática da equoterapia. Materiais e métodos : estudo experimental, clínico, pré e pós-teste.
Tiago Toigo   +2 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Synthetic vs Human Emotional Faces: What Changes in Humans' Decoding Accuracy [PDF]

open access: yesarXiv
Considered the increasing use of assistive technologies in the shape of virtual agents, it is necessary to investigate those factors which characterize and affect the interaction between the user and the agent, among these emerges the way in which people interpret and decode synthetic emotions, i.e., emotional expressions conveyed by virtual agents ...
arxiv  

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