We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová+14 more
wiley +1 more source
Rural-urban differences in lipid abnormalities among middle-aged and older Indians. [PDF]
Chatterjee P+5 more
europepmc +1 more source
VIII. Two Letters from George Godwin, Esq. F.R.S. & F.S.A. to Sir Henry Ellis, K.H., F.R.S., Secretary, on certain Marks discoverable on the Stones of various Buildings erected in the Middle Ages [PDF]
George Godwin
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YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
Determinants of depressive symptoms in multinational middle-aged and older adults. [PDF]
Lu C, Wan S, Liu Z.
europepmc +1 more source
Science and literature in the Middle Ages and at the period of the Renaissance
P. L. Jacob
openalex +2 more sources
Cambridge Economic History of Europe, The. Vol. II: Trade and Industry in the Middle. Ages. Edited by M. Postan and E. E. Rich. Pp. xvi, 604. New York: Cambridge University Press, 1952. $14.00 [PDF]
Joseph R. Strayer
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We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin+10 more
wiley +1 more source