Results 151 to 160 of about 12,195,030 (401)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Emotional Symptoms and Health Complaints for Patients Seeking Psychomotor Physiotherapy
Aim: Because patients seeking Norwegian psychomotor physiotherapy (PMF) rarely have been described with validated, psychometrically sound instruments, we used six questionnaires to characterize these patients in terms of subjective health complaints and ...
Monica H. Breitve +2 more
doaj
Resumo Objetivo : Mensurar a melhora do equilíbrio estático em indivíduos da terceira idade com a prática da equoterapia. Materiais e métodos : estudo experimental, clínico, pré e pós-teste.
Tiago Toigo +2 more
doaj +1 more source
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men.
H. Lakka +6 more
semanticscholar +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Purpose: Disturbances in balance and also regaining the balance strategy is very important in the middle-aged women who are near their menopause and subject to severe hormonal and physiological changes, reduced muscle strength, and decreased bone density.
Niloufar Rahmani +2 more
doaj
Older Workers and On-the-Job Training in Canada: Evidence from the WES Data [PDF]
This paper provides evidence of on-the-job training among older workers in Canada. It also examines the effect of age associated with on-the-job training.
G.B. Cooke, I.U. Zeytinoglu, K. Harry
core
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source

