Results 221 to 230 of about 11,022,196 (359)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Epidemiology of Myocarditis in Young and Middle-Aged Population in Asia. [PDF]

JACC Asia
Li C, Lu Z, Wang DW.
europepmc   +1 more source

Benefits of having friends in older ages: differential effects of informal social activities on well-being in middle-aged and older adults.

The journals of gerontology. Series B, Psychological sciences and social sciences, 2014
O. Huxhold, M. Miche, B. Schüz
semanticscholar   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013–2014 influenza season

Proceedings of the National Academy of Sciences of the United States of America, 2014
Susanne L. Linderman, Benjamin S Chambers, Seth J. Zost, Kaela Parkhouse, Yang Li, Christina Herrmann, A. Ellebedy, Donald M. Carter, Sarah F. Andrews, Nai-Ying Zheng, Min Huang, Yunping Huang, D. Strauss, B. Shaz, R. Hodinka, G. Reyes-Terán, T. Ross, P. Wilson, R. Ahmed, J. Bloom, S. Hensley   +20 more
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Food-addiction scale measurement in 2 cohorts of middle-aged and older women.

American Journal of Clinical Nutrition, 2014
A. Flint, A. Gearhardt, W. Corbin, K. Brownell, A. Field, E. Rimm   +5 more
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Correction: Rural-urban differences in lipid abnormalities among middle‑aged and older Indians. [PDF]

BMC Public Health
Chatterjee P, Arora S, Rai P, Diwakar L, Issac TG, Sundarakumar JS.   +5 more
europepmc   +1 more source