Results 231 to 240 of about 12,195,030 (401)
Independent and Combined Effects of Household Solid Fuel Use and Outdoor PM2.5 on Mental Health among Reproductive-aged Women in Low- and Middle-Income Countries [PDF]
Muhammad Mainuddin Patwary +2 more
openalex +1 more source
Resilience, Coping Methods, and Quality of Life in Middle-aged Women [PDF]
, 2011 Myung Sill Chung
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Genetic Contribution to the P3 in Young and Middle-Aged Adults [PDF]
, 2007 Dirk J. A. Smit +3 more
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Epidemiology of Myocarditis in Young and Middle-Aged Population in Asia. [PDF]
JACC AsiaLi C, Lu Z, Wang DW.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source