Results 251 to 260 of about 12,195,030 (401)

ASSOCIATION OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AND C- REACT IVE PROTEIN WITH MODERATE-TO-VIGOROUS PHYSICAL ACTIVITY IN MIDDLE-AGED WOMEN [PDF]

, 2011
David J. Rice
openalex  

Utilization patterns of antidepressants between 1991 and 2011 in a population-based cohort of middle-aged and elderly

, 2014
Nikkie Aarts, Raymond Noordam, Albert Hofman, Henning Tiemeier, Bruno H. Stricker, Loes E. Visser   +5 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Smoking cessation among middle-aged and older adults in India. [PDF]

Sci Rep
Kodali PB, Maniyara K, Palle E.
europepmc   +1 more source

Identification of late-onset hypogonadism in middle-aged and elderly men.

New England Journal of Medicine, 2010
Frederick C W Wu, A. Tajar, J. Beynon, S. Pye, A. Silman, J. Finn, T. O’Neill, G. Bártfai, F. Casanueva, G. Forti, A. Giwercman, T. Han, K. Kula, M. Lean, N. Pendleton, M. Punab, S. Boonen, D. Vanderschueren, F. Labrie, I. Huhtaniemi   +19 more
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Acute impact of first-time marathon running on the heart in middle-aged men. [PDF]

Open Heart
Laily I, van Steijn N, Wiggers TGH, Froeling M, Planken RN, Verwijs SM, de Haan FH, Motazedi E, Verhagen EALM, Jørstad HT, Bakermans AJ.   +10 more
europepmc   +1 more source

Insulin resistance predicts brain amyloid deposition in late middle-aged adults

Alzheimer's & Dementia, 2015
A. Willette, Sterling C. Johnson, A. Birdsill, M. Sager, Bradley Christian, L. Baker, S. Craft, Jennifer M. Oh, E. Statz, B. Hermann, E. Jonaitis, R. Koscik, A. L. Rue, S. Asthana, B. Bendlin   +14 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Factors Associated with the Middle-aged or the Old-aged Koreans' Enrollment in Private Health Insurance

, 2012
Hyojin Kim, Lee Jae-hee
openalex   +2 more sources