Results 31 to 40 of about 1,480,064 (291)

Frequency of Nocturnal Leg Cramp Symptoms and Gender Comparison of Stress, Physical Activity and Sleep Disturbances in Middle Aged Adults with Nocturnal Leg Cramps

Türk Uyku Tıbbı Dergisi, 2022
Objective:Nocturnal leg cramps are painful, sleep related involuntary muscle contractions of the lower limb. The objective was to determine the frequency of nocturnal leg cramp symptoms and to compare stress, sleep disturbances, and physical activity ...
Sarah Khan, Sania Sohail, Hania Farheen, Tahir Ramzan, Iqra Imtiaz, Zoya Mehmood   +5 more
doaj   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

Population Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The aging process and health: what middle-aged people think of the issue

Revista Brasileira de Geriatria e Gerontologia
Objective To understand the perception of middle-aged adults regarding health and the aging process. Method A qualitative study involving 30 adults aged 45 to 59 years old, 15 of whom were female and 15 of whom were male, who answered open questions ...
Fernanda Rigoto Mari, Gehysa Guimarães Alves, Denise Rangel Ganso de Castro Aerts, Sheila Camara   +3 more
doaj   +1 more source

Perceptions of andropausal experience types among middle-aged men—applying the Q methodology [PDF]

Journal of Men's Health
Background: This study seeks to utilize the Q methodology to identify distinct typologies of andropausal experience perception among middle-aged men, with the goal of comprehending their understanding of andropausal experiences. Methods: The aim is to
Young Sook Lim, Sun Jung Park
doaj   +1 more source

Prevalence of risk factors for dementia in middle- and older- aged people registered in Primary Health Care

Dementia & Neuropsychologia, 2021
. It is important to assess the prevalence of risk factors for dementia to slow down the progression and evolution of the disease, and to support interventions and prevention programs.
Bruna Moretti Luchesi, Beatriz Rodrigues de Souza Melo, Priscila Balderrama, Aline Cristina Martins Gratão, Marcos Hortes Nisihara Chagas, Sofia Cristina Iost Pavarini, Tatiana Carvalho Reis Martins   +6 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Seasonal impact of diurnal temperature range on intracerebral hemorrhage in middle-aged and elderly people in central China [PDF]

Epidemiology and Health
OBJECTIVES This study investigated the seasonal impact of diurnal temperature range (DTR) on hospitalization rates for intracerebral hemorrhage (ICH) in middle-aged and elderly adults.
Shiwen Wang, Jinyu Yin, Hao Zhou, Jingmin Lai, Guizhen Xiao, Zhuoya Tong, Jing Deng, Fang Yang, Qianshan Shi, jingcheng shi   +9 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source