Results 41 to 50 of about 1,533,855 (292)
The aging process and health: what middle-aged people think of the issue
Revista Brasileira de Geriatria e GerontologiaObjective To understand the perception of middle-aged adults regarding health and the aging process. Method A qualitative study involving 30 adults aged 45 to 59 years old, 15 of whom were female and 15 of whom were male, who answered open questions ...
Fernanda Rigoto Mari +3 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Work measurement and time study of the middle-aged health self-care program by Iranian Ministry of Health [PDF]
PayeshObjective(s): Work measurement and time study of services offer insights into human resource management and workload and is crucial for accurate human resource estimation.
Afsoon Aeenparast +6 more
doaj
Dataset of youth and middle-aged unemployment in households in Kwara State, Nigeria
Data in BriefThis article shares the findings from survey conducted between November 2021 and April 2022 across the three senatorial districts of Kwara state, Nigeria.
Adebayo Mohammed Ojuolape +2 more
doaj +1 more source
Asian Nursing Research, 2016 Purpose: In Korea, most elderly with dementia receive care from family members, yet little research is available on the experience of dementia-related anxiety in middle-aged female caregivers for a family member with dementia.
Jeong Sun Kim, RN, PhD +2 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Asian Nursing Research, 2021 Purpose: This study aimed at developing a happiness assessment scale for middle-aged women (HAS-MW) in Korea. Methods: Preliminary items for the scale were drafted from the results of literature review and personal interviews and open-ended questions ...
Hee-Jin Shin, Jeung-Im Kim
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Normative data for middle-aged Brazilians in the Mattis Dementia Rating Scale
Dementia & Neuropsychologia, 2020 . Despite the advances in the diagnosis of dementia, neuropsychological assessment remains an important tool. The Mattis Dementia Rating Scale (DRS) was designed to evaluate people with suspected dementia and allows for the analysis of different ...
Guilherme Almeida Carvalho +1 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source