Results 51 to 60 of about 1,480,064 (291)

Oral function is associated with the body and muscle mass indices of middle‐aged dental patients

open access: yesClinical and Experimental Dental Research, 2022
Objectives Undernutrition is associated with frailty, one of the common reasons for seeking long‐term care. In older adults, nutritional status is known to be associated with oral function; however, it is not yet known if there is a similar association ...
Tomotaka Nishi   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Normative data for middle-aged Brazilians in the Mattis Dementia Rating Scale

open access: yesDementia & Neuropsychologia, 2020
. Despite the advances in the diagnosis of dementia, neuropsychological assessment remains an important tool. The Mattis Dementia Rating Scale (DRS) was designed to evaluate people with suspected dementia and allows for the analysis of different ...
Guilherme Almeida Carvalho   +1 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Development and Validation of the Happiness Scale for Middle-Aged Women Based on Existence, Relation, and Growth Theory

open access: yesAsian Nursing Research, 2021
Purpose: This study aimed at developing a happiness assessment scale for middle-aged women (HAS-MW) in Korea. Methods: Preliminary items for the scale were drafted from the results of literature review and personal interviews and open-ended questions ...
Hee-Jin Shin, Jeung-Im Kim
doaj  

Meaning of Happiness Based on ERG Theory in Middle-Aged Korean Women [PDF]

open access: yesKorean Journal of Women Health Nursing, 2019
PURPOSE: The purpose of this study was to explore the components and nature of happiness in middle-aged women in Korea. METHODS: Thirty middle-aged women living in metropolitan Seoul and Gyeonggi and Chungcheong provinces agreed to participate in this ...
Hee Jin Shin, Jeung Im Kim
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

A Study on Body Image, Sexual Quality of Life, Depression, and Quality of Life in Middle-aged Adults

open access: yesAsian Nursing Research, 2015
Purpose: The purpose of this study was to examine the correlations of body image, sexual quality of life (SQOL), depression, and quality of life, and to identify the influencing factors on quality of life of middle-aged adults in the community.
Jeong Sun Kim, PhD, RN   +1 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

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