Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals
BackgroundHuman aging is associated with profound changes in one of the major epigenetic mechanisms, DNA methylation. Some of these changes occur in a clock-like fashion, i.e., correlating with the calendar age of an individual, thus providing a new ...
T. Nevalainen +10 more
semanticscholar +1 more source
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo +5 more
wiley +1 more source
The aging process and health: what middle-aged people think of the issue
Objective To understand the perception of middle-aged adults regarding health and the aging process. Method A qualitative study involving 30 adults aged 45 to 59 years old, 15 of whom were female and 15 of whom were male, who answered open questions ...
Fernanda Rigoto Mari +3 more
doaj +1 more source
Normative data for middle-aged Brazilians in the Mattis Dementia Rating Scale
. Despite the advances in the diagnosis of dementia, neuropsychological assessment remains an important tool. The Mattis Dementia Rating Scale (DRS) was designed to evaluate people with suspected dementia and allows for the analysis of different ...
Guilherme Almeida Carvalho +1 more
doaj +1 more source
Insomnia disorder increases the risk of subjective memory decline in middle-aged and older adults: a longitudinal analysis of the Canadian Longitudinal Study on Aging [PDF]
Jean-Louis Zhao +7 more
openalex +1 more source
Influence of estimated training status on anti and pro-oxidant activity, nitrite concentration, and blood pressure in middle-aged and older women [PDF]
The purpose of this study was to compare the association between anti and pro-oxidant activity, nitrite concentration, and blood pressure (BP) in middle-aged and older women with different levels of estimated training status (TS). The sample consisted of
Amaral, Sandra L. +8 more
core +1 more source
Clinical Correlates of Anxiety and Depression After Diagnosis of a Pediatric Brain Tumor
ABSTRACT Background The prevalence and clinical correlates of symptoms of anxiety and depression in pediatric patients with brain tumors are not well described. We aimed to identify clinical characteristics that are correlated with elevated symptoms of anxiety and depression following initial diagnosis.
Bryony J. Lucas +16 more
wiley +1 more source
Revisiting Adult Playfulness and Relationship Satisfaction: APIM Analyses of Middle-Aged and Older Couples [PDF]
Kay Brauer +4 more
openalex +1 more source
Recently, gamma-ray telescopes AGILE and Fermi observed several middle-aged supernova remnants (SNRs) interacting with molecular clouds. It is likely that their gamma rays arise from the decay of neutral pions produced by the inelastic collision between ...
Abdo +53 more
core +1 more source
Health-related quality of life is low in secondary school children in Fiji [PDF]
The health and wellbeing of children in lower-income countries is the focus of much international effort, yet there has been very little direct measurement of this. Objective.
Goundar, Ramneek +5 more
core +2 more sources

