Results 71 to 80 of about 10,435,023 (317)
PLoS ONE, 2015 To elucidate the effects of endurance training on circulating irisin levels in young and middle-aged/older adults, and to determine the association between endurance training-induced alteration of irisin and reduction in body fat.
E. Miyamoto-Mikami +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
X-ray Emission from Middle-Aged Gamma-Ray Pulsars [PDF]
arXiv, 2015 Electrons/positrons produced in a pulsar magnetosphere emit synchrotron radiation, which is widely believed as the origin of the non-thermal X-ray emission detected from pulsars. Particles are produced by curvature photons emitted from accelerated particles in the magnetosphere. These curvature photons are detected as pulsed $\gamma$-ray emissions from
arxiv
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Journal of Clinical Endocrinology and Metabolism, 2002 We used longitudinal data from the Massachusetts Male Aging Study, a large population-based random-sample cohort of men aged 40-70 yr at baseline, to establish normative age trends for serum level of T and related hormones in middle-aged men and to test ...
H. Feldman +7 more
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
The Transition from Young to Middle-aged Supernova Remnants: Thermal and Nonthermal Aspects of SNR N132D [PDF]
, 2018 Supernova remnants (SNRs) are the primary candidate of Galactic cosmic-ray accelerators. It is still an open issue when and how young SNRs, which typically exhibit strong synchrotron X-rays and GeV and TeV gamma-rays, undergo the state transition to middle-aged SNRs dominated by thermal X-rays and GeV gamma-rays.
arxiv +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source