Results 101 to 110 of about 476,712 (311)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
On the Occurrence of Retinal Hemorrhage after Middle Age, and Its Bearing on the Duration of Life [PDF]
Hasket Derby
openalex +1 more source
'Deliver This Horse from Evil': The Ritual Aspects of Responses to Veterinary Disease in the Late Middle Ages. [PDF]
Harrison S.
europepmc +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
The Effect of an Ordinary Meal on the Electrocardiogram. Normal Standards in Middle-Aged Men and Women [PDF]
Ernst Simonson, Ancel Keys
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Градът Карвуна? (Извори и археология)
This study reviews all available sources and publications about the territory known in the 11th–14th century under the name of the Karvuna land (Karvunskata zemya), Karvona chora, Karvuna archontate and the town of Karvuna.
Valentin Pletnyov
doaj
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Presenting Medieval Gambling and Pub Life
There are many legendary games in the Middle Ages with professed losses of clothes, horses and, what is more, whole estates, and even halves of kingdoms. But was money really the most important part of gambling?
Zsuzsanna Sőregi
doaj