A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
“A Mirror for Men” – Reconstructing a Medieval Polishing Bench and Putting it to the Test
In the late 5th century AD, the famous Ostrogoth Theoderic the Great received a truly regal gift from the king of the Warini: he was given highly elaborated swords, richly decorated and able to cut through armour.
Florian Messner
doaj
Correction to: The Medical Historical Cultural Foundations of Western Nasal Surgery from Ancient Greece to the Middle Ages. [PDF]
Marinozzi S +6 more
europepmc +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Biomechanical Asymmetry of Strength and Dynamic Balance Kinetics in Middle-Ages with Adhesive Capsulitis of the Hip. [PDF]
Choi M, Kim Y.
europepmc +1 more source
Prevalence of High-Burden Medical Conditions Among Young and Middle-Aged Adults With Pediatric-Onset Medical Conditions: Findings From US Private and Public Administrative Claims Data [PDF]
Daniel G. Whitney
openalex +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
L’épineuse lecture du « trône de Dagobert » : analyses techniques, stylistiques et matérielles
The “throne of Dagobert” is one of the most famous pieces of medieval furniture in Western Europe. Discovered in the first half of the 12th c. by Suger, abbot of Saint-Denis, it was linked to the last great Merovingian king Dagobert. However, its precise
Cécile Lagane, Lise Saussus
doaj +1 more source
Funnel-shaped glasses have been found in several places, for example in Birka (graves 577, 526, 551, 850, 854, 464, 849 and 433), Sweden and in the Netherlands (De Heul, Utrecht collection PUG).
Karl Jakob Lamberth
doaj

