Results 121 to 130 of about 10,834,348 (379)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Glass Lamps, a Few Points

open access: yesEXARC Journal, 2023
Funnel-shaped glasses have been found in several places, for example in Birka (graves 577, 526, 551, 850, 854, 464, 849 and 433), Sweden and in the Netherlands (De Heul, Utrecht collection PUG).
Karl Jakob Lamberth
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

4. Roger Bacon and Medieval Science

open access: yes, 1958
Throughout the Middle Ages there was little interest in theoretical science as such. Not since the Greeks had nature been considered a sufficient object in and of itself for most of the study that we would call scientific.
Bloom, Robert L.   +6 more
core  

Theological methods in the middle ages

open access: yesCuestiones Teológicas, 2020
To speak of the methods of theology in the Middle Ages means to recognize the coexistence of pluriform methodological and epistemological postures in theology.
José Alfredo Noratto Gutiérrez
doaj  

The Medical Historical Cultural Foundations of Western Nasal Surgery from Ancient Greece to the Middle Ages. [PDF]

open access: yesAesthetic Plast Surg, 2023
Marinozzi S   +6 more
europepmc   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

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