Results 131 to 140 of about 1,771,516 (307)
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Presenting Medieval Gambling and Pub Life
There are many legendary games in the Middle Ages with professed losses of clothes, horses and, what is more, whole estates, and even halves of kingdoms. But was money really the most important part of gambling?
Zsuzsanna Sőregi
doaj
4. Roger Bacon and Medieval Science
Throughout the Middle Ages there was little interest in theoretical science as such. Not since the Greeks had nature been considered a sufficient object in and of itself for most of the study that we would call scientific.
Bloom, Robert L. +6 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Градът Карвуна? (Извори и археология)
This study reviews all available sources and publications about the territory known in the 11th–14th century under the name of the Karvuna land (Karvunskata zemya), Karvona chora, Karvuna archontate and the town of Karvuna.
Valentin Pletnyov
doaj
Living Standards and Mortality since the Middle Ages [PDF]
Existing studies find little connection between living standards and mortality in England, but go back only to the sixteenth century. Using new data on inheritances, we extend estimates of mortality back to the mid-thirteenth century and find, by ...
Cormac Ó Gráda, Morgan Kelly
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Brewing cultures in early modern towns : an introduction [PDF]
Since Antiquity, fermented drinks have played an important role in European culture. In eastern and northern areas, ale - and from the close of the Middle Ages hopped beer - formed part of people's diets, provided livelihoods for rural alewives as ...
Kümin, Beat A.
core

