Results 161 to 170 of about 431,140 (262)

Distinct epigenomes in CD4⁺ T cells of newborns, middle-ages and centenarians. [PDF]

Sci Rep, 2016
Zhao M, Qin J, Yin H, Tan Y, Liao W, Liu Q, Luo S, He M, Liang G, Shi Y, Zhang Q, Cai W, Yin G, Zhou Y, Wang J, Li M, Huang Y, Liu A, Wu H, Zhang Z, Lu Q.   +20 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Polyphasic analysis of a middle ages coprolite microbiota, Belgium. [PDF]

PLoS One, 2014
Appelt S, Armougom F, Le Bailly M, Robert C, Drancourt M.   +4 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Preface: Living, Creating, Storytelling and Writing in the Middle Ages

Nalans, 2022
Mustafa Zeki Çıraklı
doaj  

[Urology in Upper Palatinate-what archeology, historical research, and historiography reveal : Part 1: from Roman Antiquity to the late Middle Ages]. [PDF]

Urologie
Otto W.
europepmc   +1 more source

Footprints of middle ages kingdoms are still visible in the contemporary surname structure of Spain. [PDF]

PLoS One, 2015
Rodríguez-Díaz R, Manni F, Blanco-Villegas MJ.   +2 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Intensive woodland management in the Middle Ages: spatial modelling based on archival data. [PDF]

J Hist Geogr, 2015
Szabó P, Müllerová J, Suchánková S, Kotačka M.   +3 more
europepmc   +1 more source