Results 241 to 250 of about 11,148,453 (358)

The Middle Ages Contributions to Cardiovascular Medicine. [PDF]

open access: yesBraz J Cardiovasc Surg, 2016
Ranhel AS, Mesquita ET.
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Spotted phenotypes in horses lost attractiveness in the Middle Ages. [PDF]

open access: yesSci Rep, 2016
Wutke S   +16 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Habitual hot water bathing protects cardiovascular function in middle-aged to elderly Japanese subjects [PDF]

open access: gold, 2018
Katsuhiko Kohara   +7 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. [PDF]

open access: yesSci Rep, 2016
Zhao M   +20 more
europepmc   +1 more source

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