Results 261 to 270 of about 11,148,453 (358)
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Mondino de Luzzi: a luminous figure in the darkness of the Middle Ages. [PDF]
Mavrodi A, Paraskevas G.
europepmc +1 more source
Cerebral/Peripheral Vascular Reactivity and Neurocognition in Middle-Age Athletes
Takashi Tarumi +7 more
openalex +1 more source
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Alcohol intake and brain white matter in middle aged men: Microscopic and macroscopic differences
Linda K. McEvoy +10 more
openalex +1 more source
Gerald of Wales and Competing Interpretations of the Welsh Middle Ages c. 1870-1910 [PDF]
Marsden, Richard
core
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Dante and asthenopia: a modern visual problem described during the Middle Ages. [PDF]
Riva MA, Arpa C, Gioco M.
europepmc +1 more source

