Results 21 to 30 of about 11,148,453 (358)

Trends and correlates of marijuana use among late middle-aged and older adults in the United States, 2002–2014 [PDF]

open access: yes, 2017
BACKGROUND: Recent trend studies suggest that marijuana use is on the rise among the general population of adults ages 18 and older in the United States.
AbiNader, Millan   +6 more
core   +1 more source

The Early Christians in the Face of Epidemics

open access: yesStudia Ceranea, 2021
The purpose of the article is to present the reaction of the early Christians to the emergence and the spread of the great epidemics. During the early Christian ages (2nd–3rd centuries) different plagues devastated people of the Roman Empire ...
Oleksandr Kashchuk
doaj   +1 more source

Greek-Arabic-Latin: The transmission of mathematical texts in the Middle Ages [PDF]

open access: yes, 2001
During the Middle Ages many Greek mathematical and astronomical texts were translated from Greek into Arabic (ca. ninth century) and from Arabic into Latin (ca. twelfth century). There were many factors complicating the study of them, such as translation
Lorch, Richard
core   +1 more source

A risk society? Environmental hazards, risk and resilience in the later Middle Ages in Europe

open access: yesNatural Hazards, 2013
Modern society is said to have restructured in reaction to contemporary hazards with the aim of improving its management of risk. This implies that pre-industrial societies were somehow fundamentally different. In this paper, we challenge that hypothesis
C. Gerrard, D. Petley
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Dark and Middle Ages [PDF]

open access: yes, 2018
For the most part only Plato\u27s teachings supported by a limited version of Aristotelian cosmology supportive of Platonism survived the decline of ancient Greek philosophy during the Roman Empire. Christianity later prevailed, and toward the end of the
Jayne, Edward
core   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Everyman with fangs: The acceptance of the modern vampire [PDF]

open access: yes, 2007
The vampire, an enduring demon from the European middle ages has through the course of the 20th century undergone a journey of transformation. The journey of the beast describes a circle, starting and ending with the depiction of the vampire as a ...
Cardow, Andrew
core  

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

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