Results 31 to 40 of about 476,712 (311)
Recreating Historic European Spindle Spinning
EXARC Journal, 2021 Spinning is a vital step in the production of textiles, whereby fibres are drawn out (drafted) and twisted together to make thread. In the present day, several culturally unique types of spinning are recognised, such as the thigh-rolling technique of ...
Mary Ann Megan Cleaton +3 more
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Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Приноси към българската археология, 2018 The article presents: – the opinions on the construction of the basilicas excavated in Chersoneses/Kherson (Crimea) for a construction period of 150 years: the 5th – early 7th century or the 6th – the mid 7th century; – the epigraphic information
Alla Romanchuk
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Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Heritage ScienceIn addition to his astronomical observations the famous Renaissance astronomer Tycho Brahe (1546–1601) was known also for his interest in alchemy. He equipped his castle Uraniborg on the island of Ven with a state-of-the-art alchemical laboratory when it
Kaare Lund Rasmussen +1 more
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Archéologie Médiévale, 2023 In 2017, the foundations of a large church were unearthed on the plateau des Garaffes in Elne (Pyrénées-Orientales – France), 20 m east of the Romanesque cathedral built from the 11th century onwards. Its dating (6th-7th century) and size suggest that it
Olivier Passarrius +5 more
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FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Internet Archaeology, 2016 During the Middle Ages hair was charged with cultural meaning. Hair possesses various qualities that allow it to be a tool of social action; it is detachable, renewable and can be manipulated (Firth 1973). As a malleable body part it can be shaped, dyed,
Kimberley Knight
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