Results 51 to 60 of about 10,907,811 (379)
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
POST-PRESENT MIDDLE AGES AND GLOBAL TRANSFORMATIONS
Purpose To investigate globalization as the socio-cultural phenomenon of dichotomizing property and on this basis to prove medieval analogies in prospects of modern societies development.
Savtchenko Irina Aleksandrovna
doaj +2 more sources
The roots of "Western European societal evolution". A concept of Europe by Jenő Szűcs [PDF]
Jenő Szűcs wrote his essay entitled Sketch on the three regions of Europe in the early 1980s in Hungary. During these years, a historically well-argued opinion emphasising a substantial difference between Central European and Eastern European societies ...
Anderson P.+34 more
core +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
During the Middle Ages hair was charged with cultural meaning. Hair possesses various qualities that allow it to be a tool of social action; it is detachable, renewable and can be manipulated (Firth 1973). As a malleable body part it can be shaped, dyed,
Kimberley Knight
doaj +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Book review: the Middle Ages [PDF]
In Johannes Fried’s The Middle Ages, the author makes his case for an alternative interpretation of the medieval period as much more sophisticated than commonly thought, writes Ignas Kalpokas.
Kalpokas, Ignas
core
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Volhynian Provenance of the Radziwill Chronicle: Hypothesis and Its Critical Assessment
The Radziwill chronicle is a unique Cyrillic manuscript dating back to the late 15th century. It was named after Radziwill princely family who kept it in the mid-17th century.
Olena Rusyna
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