Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Exploitation d’arbustes aux périodes romaine et médiévale. Branchages des puits de Marne-La-Vallée
Archéopages, 2012 The quantity of branches recovered in preventive excavations at Marne-la-Vallée warrants a summary and synthesis of the results of their study. For practical reasons, three different wood specialists have examined assemblages that were close in time and ...
Julien Dez +2 more
doaj +1 more source
Flooding in Northern Italy during the Early Middle Ages: resilience and adaptation [PDF]
, 2015 open1Alluvial phenomena are well documented by archaeologists all over Northern Italy, and have been often linked to events reported by literary sources (e.g. the flooding of 589 described by Paul the Deacon). This paper will discuss, on the basis of the
Brogiolo, Gian Pietro
core
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Improved Aerobic Capacity and Adipokine Profile Together with Weight Loss Improve Glycemic Control without Changes in Skeletal Muscle GLUT-4 Gene Expression in Middle-Aged Subjects with Impaired Glucose Tolerance [PDF]
, 2022 Mika Venojärvi +4 more
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Domains of application and 'Skopos' of the German Cato translations in the late middle ages [PDF]
, 2010 When we look for evidence of multilingualism in the Middle Ages, we will eventually find the type of source which consists of the translation of Latin classroom texts into various vernaculars.
Baldzuhn, Michael, Haag, Guntram
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
, 1958 Between the end of the High Middle Ages (about 1350) and the Protestant Reformation in the sixteenth century, the character of Western Civilization was profoundly altered. Earlier chapters have already told how most institutions and values characteristic
Bloom, Robert L. +6 more
core
Detrital-zircon geochronology and provenance of the Ocloyic synorogenic clastic wedge, and Ordovician accretion of the Argentine Precordillera terrane [PDF]
, 2015 The Precordillera terrane in northwestern Argentina is interpreted to be anexotic (Laurentian) continental fragment that was accreted to western Gondwanaduring the Ordovician. One prominent manifestation of the subductionand collision process is a Middle?
Astini, Ricardo Alfredo +3 more
core +1 more source