Results 61 to 70 of about 476,712 (311)
La frontière dans les généalogies du Libro Verde de Aragón
Les Cahiers de Framespa, 2015 The three thousand characters of Libro Verde de Aragón –a genealogical collection describing the descendants of Aragonese Jews converted around 1400– had good reasons of crossing the borders of kingdom of Aragon.
Monique Combescure Thiry +1 more
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
India Traders of the Middle Ages
American Journal of Islam and Society, 2009 Throughout Antiquity, the Middle Ages, and our current era, the Indian Ocean has been the economic backbone of an interconnected global community. This inter-territorial commerce, which feeds a vast network of merchants from the western Mediterranean to ...
Isa Blumi
doaj +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Dyspepsia in the middle ages: a reference in Giovanni Boccaccio's Decameron (14th century AD)? [PDF]
Acta Biomed, 2023 Galassi FM +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Ancestry and kinship in a Late Antiquity-Early Middle Ages cemetery in the Eastern Italian Alps. [PDF]
iScience, 2023 Coia V +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source