Results 61 to 70 of about 10,834,348 (379)

Game of Thrones: imagined world combines romantic and grotesque visions of Middle Ages [PDF]

open access: yes, 2018
OU historian Richard Marsden examines how longstanding assumptions about the Middle Ages have shaped the world presented in HBO's Gamer of ...
Marsden, Richard
core  

The Provenance of the Radziwill Chronicle

open access: yesКиївські історичні студії
The Radziwill chronicle is a unique illuminated Cyrillic manuscript of the late 15th century. Its miniatures cover historical period from the mythical beginnings of Rus’ up to the early 13th century.
Olena Rusyna
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Presentazione [PDF]

open access: yesParole Rubate, 2019
Introduction
Francesco Bonelli   +2 more
doaj  

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Assembling the archaeology of the global Middle Ages [PDF]

open access: yes, 2017
Responding to recent developments in archaeological theory and growing interest in the ‘global Middle Ages’, an approach to exploring relations between local and global processes in the medieval world is proposed.
Jervis, Ben
core   +1 more source

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