Results 71 to 80 of about 10,907,811 (379)
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
, 1958 Between the end of the High Middle Ages (about 1350) and the Protestant Reformation in the sixteenth century, the character of Western Civilization was profoundly altered. Earlier chapters have already told how most institutions and values characteristic
Bloom, Robert L. +6 more
core
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Some Remarks on Averroes’ Long Commentary on the Metaphysics Book Alpha Meizon [PDF]
, 2017 Averroes, considered to be the greatest Aristotelian commentator in the Middle Ages, has written three different types of commentary on almost all the works of this great philosopher: short, middle and long.
Altuner, Ilyas
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Reti Medievali Rivista, 2010 This review article provides a short introduction on the Jewish problems in the Middle Ages and a systematic description of the bibliographic sources and electronic resources.
Alessandra Veronese
doaj
Comic Books Featuring the Middle Ages
Itinéraires, 2010 This article explores comic books that feature the Middle Ages as a way to show how the study of this popular media can help to further the research of the modernity of the Middle Ages.
Mónica Ann Walker Vadillo
doaj +1 more source
, 1958 The Gothic cathedral, like the Summa of Aquinas, the University of Paris, and the Christendom of Innocent III, stands as one of the major expressions of the spirit of the High Middle Ages.
Bloom, Robert L. +6 more
core
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source