Results 71 to 80 of about 476,712 (311)

From the Soil to the Iron Product - the Technology of Medieval Iron Smelting

open access: yesEXARC Journal, 2014
2013 EXARC meeting at Csiki Pihenökert (HU) Nowadays, the development of technology rushes past the people of the machine-based technical civilisation, therefore they fail to understand the technological wonders that surround them.
Adam Thiele
doaj  

Food globalization in southern Central Asia: archaeobotany at Bukhara between antiquity and the Middle Ages. [PDF]

open access: yesArchaeol Anthropol Sci, 2023
Mir-Makhamad B   +4 more
europepmc   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

“A Mirror for Men” – Reconstructing a Medieval Polishing Bench and Putting it to the Test

open access: yesEXARC Journal, 2020
In the late 5th century AD, the famous Ostrogoth Theoderic the Great received a truly regal gift from the king of the Warini: he was given highly elaborated swords, richly decorated and able to cut through armour.
Florian Messner
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Bruno da Longobucco (da Longoburgo): The first academic surgeon in the Middle Ages. [PDF]

open access: yesFront Surg, 2022
Pata F   +5 more
europepmc   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Correction to: The Medical Historical Cultural Foundations of Western Nasal Surgery from Ancient Greece to the Middle Ages. [PDF]

open access: yesAesthetic Plast Surg, 2023
Marinozzi S   +6 more
europepmc   +1 more source

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