Results 71 to 80 of about 1,641,556 (268)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

X-ray Emission from Middle-Aged Gamma-Ray Pulsars [PDF]

open access: yesarXiv, 2015
Electrons/positrons produced in a pulsar magnetosphere emit synchrotron radiation, which is widely believed as the origin of the non-thermal X-ray emission detected from pulsars. Particles are produced by curvature photons emitted from accelerated particles in the magnetosphere. These curvature photons are detected as pulsed $\gamma$-ray emissions from
arxiv  

The Age At Menarche In Nigerian Adolescents From Two Different Socioeconomic Classes [PDF]

open access: yes, 2008
Menarcheal age was studied in 900 girls, half of which were from middle class families and the other half from low income class families from the Niger delta region of Nigeria.
Ofuya, Zuleat Millicent
core   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The Transition from Young to Middle-aged Supernova Remnants: Thermal and Nonthermal Aspects of SNR N132D [PDF]

open access: yes, 2018
Supernova remnants (SNRs) are the primary candidate of Galactic cosmic-ray accelerators. It is still an open issue when and how young SNRs, which typically exhibit strong synchrotron X-rays and GeV and TeV gamma-rays, undergo the state transition to middle-aged SNRs dominated by thermal X-rays and GeV gamma-rays.
arxiv   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Il medioevo citato di Giovanni Pascoli. Re Enzo fra storia e simbolo [PDF]

open access: yesParole Rubate, 2019
This essay examines Giovanni Pascoli’s Canzoni di Re Enzio within the nineteenth-century context of medieval revival. Far from stylizations and adaptations, the philological precision of the evocation of historical facts is linked to the tragedy of human
Francesca Irene Sensini
doaj  

Comic Books Featuring the Middle Ages

open access: yesItinéraires, 2010
This article explores comic books that feature the Middle Ages as a way to show how the study of this popular media can help to further the research of the modernity of the Middle Ages.
Mónica Ann Walker Vadillo
doaj   +1 more source

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