Results 91 to 100 of about 13,529 (354)

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng   +17 more
wiley   +1 more source

Settlement dynamics in the Lower Mureș Region during the 2nd millennium BCE

open access: yesCommunicationes Archaeologicae Hungariae
The Lower Mureș Region (LMR) is a distinct geographical area in the southeastern part of the Carpathian Basin. It stretches from where the Mureș River exits the mountain corridor to its confluence with the Tisza River. Systematic field surveys conducted
Victor Sava, Florin Gogâltan
doaj   +1 more source

Closed‐Loop Radiative Cooling Mulch Upcycled From Agricultural Residues for Efficient Soil Heat–Water Stress Mitigation

open access: yesAdvanced Science, EarlyView.
Conventional passive radiative cooling films rely on costly feedstocks and energy‐intensive fabrication, with poor end‐of‐life compatibility in agriculture. To address this challenge, a sustainable radiative cooling mulch (SRCM) is developed from waste maize leaves via spontaneous hydrogen‐bond self‐assembly.
Hao Li   +13 more
wiley   +1 more source

Large-scale migration into Britain during the Middle to Late Bronze Age

open access: yesNature, 2021
N. Patterson   +222 more
semanticscholar   +1 more source

Manufacturing and trade of Asian elephant ivory in Bronze Age Middle Asia. Evidence from Gonur Depe (Margiana, Turkmenistan)

open access: yesArchaeological Research in Asia, 2017
This paper presents the detailed stylistic and functional analysis of a large collection of artifacts made from Asian elephant ivory discovered at the Oxus Civilization site of Gonur Depe in southern Turkmenistan.
D. Frenez
semanticscholar   +1 more source

SOME WAYS OF TALUSES' USE IN FUNERAL RITE OF EARLY AND MIDDLE BRONZE AGE PEOPLE

open access: yesRUDN Journal of World History, 2014
The aim of this article is the analysis of small cattle’s taluses that were found in funeral complexes in Donetz river region dated by Early and Middle Bronze age.
A N Usachuk, N V Panasyuk
doaj  

A Network Proposal for the Caput Adriae in the Middle and Recent Bronze Ages (MBA2 - RBA1)

open access: yesIpoTESI di Preistoria
Caput Adriae, the territory between Istria and Friuli, experienced a systematic occupation both through the spread of fortified settlements in Istria, Karst and Upper Friuli, and through the emergence of numerous open settlements in the lowlands, between
Giulio Simeoni
doaj   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

Preliminary Results on Flood Disasters in the Elbistan Plain during the Second Millennium BC: Findings from the Elbistan Karahöyük Excavations

open access: yesAnadolu Araştırmaları
Elbistan Karahöyük is located in the centre of the Karahüyük neighbourhood, 10 km northwest of the Elbistan district of Kahramanmaraş province. On the western edge of the mound flows the Hurman Stream, and on the other side is Hamzatepe, another centre ...
Bora Uysal
doaj   +1 more source

From Materials to Medical Images: Translating Perovskite‐Based X‐Ray Detectors Toward Clinical Imaging

open access: yesAdvanced Science, EarlyView.
This review examines perovskite‐based X‐ray detectors from a materials‐to‐medical‐images perspective. Recent progress in perovskite‐based X‐ray detectors is discussed with emphasis on their relevance to clinical imaging. The key barriers to clinical implementation are analyzed.
Sibin Wang   +8 more
wiley   +1 more source

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