Results 31 to 40 of about 3,490 (230)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Contribution to the mayfly, aquatic and semiaquatic bug, aquatic beetle, caddisfly and chironomid fauna of the River Tisza and its main inflows (Ephemeroptera, Heteroptera: Nepomorpha and Gerromorpha, Coleoptera: Hydradephaga and Hydrophiloidea, Trichoptera, Diptera: Chironomidae) [PDF]
, 2005 Localities and collecting data of 25 mayfly, 20 aquatic and semiaquatic bug, 49 aquatic beetle, 15 caddisfly and 55 chironomid taxa are given from 26 collecting sites of the River Tisza and its main inflows.
Csabai, Zoltán +5 more
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Zoosystematica Rossica, 2005 Kalama kiritshenkoi sp. n. from Tajikistan and Kyrgyzstan (imagines and 5th instar larvae) and Phaenotropis kobachidzei sp. n. from Georgia and Turkmenistan (imagines) are described.
openaire +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Вишенка-2 – новый чернолесско-жаботинский памятник в Среднем Побужье [PDF]
, 2004 Yu. Boyko. Visbenka-2 — New Cbemolesye-Zbabotin Antique in the Middle Bug Region The article contains the detailed analysis of results of excavation of the single VIII century B.C. hole in the excavated settlement in the Eastern Podolye.
Бойко, Ю.Н.
core +2 more sources
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Ichthyofauna Changes in the Low Dnieper and the Dnieper-Bug Estuary in Connection with Hydroconstruction [PDF]
, 1967 The construction of the cascade of reservoirs in the middle and low Dnieper and decrease of the river discharge change the hydrological regime of the low Dnieper and the Dnieper-Bug estuary: the floods are rare now, flow speed falls, the estuary becomes ...
Залуми, С.Г.
core +3 more sources