Results 131 to 140 of about 14,389 (262)

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Variation in Vessel Size and Angiographic Outcomes Following Stent‐Retriever Thrombectomy in Acute Ischemic Stroke: STRATIS Registry

Stroke: Vascular and Interventional Neurology
Background Mechanical thrombectomy is established for large‐vessel occlusions in acute ischemic stroke, but the potential role in distal vessel occlusions of medium arteries is less well established.
Hamidreza Saber, Michael T. Froehler, Osama O. Zaidat, Ali Aziz Sultan, Richard P. Klucznik, Jeffrey L. Saver, Nerses Sanossian, Frank R. Hellinger, Dileep R. Yavagal, Tom L. Yao, Reza Jahan, Diogo C. Haussen, Raul G. Nogueira, Alicia M. Hall, Nils H. Mueller Kronast, David S. Liebeskind   +15 more
doaj   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source

Cerebral Blood Transit in Sickle Cell Anemia

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Sickle cell anemia (SCA) patients upregulate cerebral blood flow to compensate for decreased arterial oxygen content. Such hyperemic conditions can manifest as venous hyperintense signal on arterial spin labeling (ASL) MRI, which may reflect faster capillary blood transit, altered oxygen extraction fraction (OEF), and infarct risk ...
Wesley T. Richerson, Megan A. Aumann, Alexander K. Song, Samantha Davis, Lauren Milner, Maria Garza, Dann Martin, L. Taylor Davis, Sumit Pruthi, Lori C. Jordan, Manus J. Donahue   +10 more
wiley   +1 more source

Microvascular Occlusion and Postrecanalization Hyperperfusion in a Swine Model of Acute Ischemic Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Despite successful recanalization after endovascular thrombectomy, more than half of patients with acute ischemic stroke with large‐vessel occlusions experience an unsatisfactory outcome.
Meiqi Wang, Aladdin Taha, Magdolna Nagy, Jadey D. Raben, Romy van Noort, Victor Volovici, Ruben Dammers, Dirk J. Duncker, Henri Spronk, Hugo ten Cate, Diederik Dippel, Joaquim Bobi, Heleen M. M. van Beusekom   +12 more
doaj   +1 more source

Impact of 1024‐Matrix Size on Perforating Artery Visualisation in Cerebral Computed Tomography Angiography Using a 64‐Slice CT Scanner

Journal of Medical Radiation Sciences, EarlyView.
This study investigated whether using a larger image matrix (1024 × 1024 pixels instead of 512 × 512) improves the visibility of tiny brain arteries on CT scans performed with standard 64‐slice scanners. While physical image quality measurements remained unchanged, the larger matrix provided finer digital sampling of blood vessel structures, resulting ...
Hokuto Nagumo, Yuki Nagata, Mayumi Maruko, Jun Sakai, Yusuke Fujiwara, Joma Oikawa   +5 more
wiley   +1 more source

Neuroprotective effects of quercetin in animal models of neurodegenerative diseases: A systematic review and meta‐analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease are characterized by progressive neuronal loss driven by oxidative stress and inflammation. Quercetin, a dietary flavonoid with established antioxidant and anti‐inflammatory properties, has emerged as a potential neuroprotective agent.
In Ho Cho, Hendra Mahakam Putra, Cheol Woon Jung, Gyu Hwan Hyun, Hwan‐Hee Jang, In Guk Hwang, Sung Won Kwon   +6 more
wiley   +1 more source

Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR‐Dependent Autophagy in the Contralateral Dentate Nucleus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Although environmental enrichment (EE) promotes post‐stroke motor recovery, the mechanisms underlying its regulation of cerebellar dentate nucleus (DN) plasticity remain unclear; this study therefore investigated how EE coordinates autophagy, mitochondrial homeostasis, and synaptic remodeling in the contralateral DN to facilitate functional ...
Chuan‐Jie Wang, Ke‐Wei Yu, Jun‐Fa Wu, Feng Tao   +3 more
wiley   +1 more source

THROMBOLYTIC TREATMENT AND DRAMATIC IMPROVEMENT OF THE CLINICAL PICTURE IN A PATIENT WITH ACUTE OCCLUSION OF THE MIDDLE CEREBRAL ARTERY FOLLOWED BY TRANSCRANIAL DOPPLER SONOGRAPHY

Zdravniški Vestnik, 2004
Background. Thrombolytic treatment of ischemic cerebral stroke by means of a recombinant tissue plasminogen activator can be very successful in selected patients.
Erih Tetičkovič, Marija Menih
doaj  

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source