Results 51 to 60 of about 110,575 (300)

Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke. [PDF]

, 2018
ObjectiveInhibitors of the voltage-gated K+ channel Kv1.3 are currently in development as immunomodulators for the treatment of autoimmune diseases. As Kv1.3 is also expressed on microglia and has been shown to be specifically up-regulated on "M1-like ...
Azam, Beeton, Beschorner, Campanella, Chen, Chen, Chen, Courties, DeCoursey, Duque, Fadool, Fordyce, Fu, Gazula, Hu, Iadecola, Jacobs, Jin, Kaushal, Kawabori, Kettenmann, Khanna, Kundu-Raychaudhuri, Longa, Lyons, Macrez, Maezawa, Maezawa, Matheu, Meisel, Murray, Nguyen, Noraberg, Pannasch, Peng, Pennington, Pereira, Price, Rangaraju, Rangaraju, Rus, Ryck, Schlattmann, Schlichter, Schmitz, Tarcha, Tarcha, Wang, Wulff, Wulff   +49 more
core   +2 more sources

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source

Sudden Coma from Acute Bilateral M1 Occlusion: Successful Treatment with Mechanical Thrombectomy

Case Reports in Neurology, 2014
We report a case with acute small infarct of the left middle cerebral artery in a 72-year-old man with atrial fibrillation documented by MRI and MR angiography.
Uwe Dietrich, Tilmann Graf, Wolf-Rüdiger Schäbitz   +2 more
doaj   +1 more source

Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review [PDF]

, 2009
Background Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke.
Alvarez-Dolado, Bath, Bath, Claire L. Gibson, Crain, Crossley, del Zoppo, Egger, England, Fisher, Gibson, Gibson, Gibson, Han, Hasselblatt, Hermann, Jendelova, Kawada, Kollmar, Komine-Kobayashi, Lan, Lee, Lees, Macleod, Matchett, Minnerup, Nagata, Philip M.W. Bath, Schabitz, Schneider, Schneider, Sehara, Sehara, Sena, Sevimli, Shuaib, Shyu, Shyu, Shyu, Six, Solaroglu, Solaroglu, Sprigg, Sprigg, Sykova, Taguchi, Timothy J. England, Toth, Vellenga, Wardlaw, Willmot, Yanqing, Zhao, Zhao, Zsebo, Zucali   +55 more
core   +2 more sources

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

A Case of Comorbid Weber Syndrome Following Mechanical Thrombectomy for Middle Cerebral Artery Occlusion

Risk Management and Healthcare Policy, 2023
Xiao-Bing Li, Hao Feng, Yi Dai, Wei Liu Department of Neurology, Beijing Haidian Hospital, Beijing, 100730, People’s Republic of ChinaCorrespondence: Wei Liu; Yi Dai, Department of Neurology, Beijing Haidian Hospital, No.
Li XB, Feng H, Dai Y, Liu W
doaj  

Changes in somatosensory evoked potentials in rats following transient cerebral ischemia

Acta Biomedica Scientifica, 2022
Background. Cerebral ischemia induced by transient middle cerebral artery occlusion is one of the most popular ischemic stroke models used to evaluate drug candidates with neuroprotective properties.
Yu. I. Sysoev, V. A. Prikhodko, I. A. Titovich, V. E. Karev, S. V. Okovityy   +4 more
doaj   +1 more source

Stent-assisted reconstructive endovascular repair of intracranial aneurysms: long-term clinical and angiographic follow-up [PDF]

, 2012
Background and Purpose: The development of self-expanding stents dedicated to intracranial use has significantly widened the applicability of endovascular therapy to many intracranial aneurysms.
VANNUCCI, STEFANO
core  

ADAMTS -1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes [PDF]

, 2006
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) enzymes are a recently described group of metalloproteinases. The substrates degraded by ADAMTS-1, -4 and -5 suggests that they play a role in turnover of extracellular matrix in the
A.K. Cross, Abbaszzade, Asher, Bandtlow, Buttini, C.J. Stock, Cardenas, Clark, Clausen, Collins-Racie, D.J. Buttle, Eddleston, G. Haddock, Hashimoto, Inatani, J. Surr, Jiang, Jones, Krekoski, Krupinski, Kuno, Kuno, Kurazono, Legos, M.N. Woodroofe, Medina-Flores, Miguel, Mulcahy, Nedergaard, Novak, Ohtaki, Pangalos, Pekny, Plumb, Porter, R.A.D. Bunning, Rawlings, Rhodes, Rosenberg, Rosenberg, Rothwell, S. Allan, Satoh, Smith, Sobel, Somerville, Tang, Tsuzaki, Vankemmelbeke, Vazquez, Wang, Yamaguchi, Yu   +52 more
core   +1 more source

Prognosis in middle cerebral artery occlusion. [PDF]

Stroke, 1985
The natural history of MCA occlusion has become increasingly important since the surgical option of EC/IC bypass surgery has been available. The clinical course of 24 patients with angiographically-demonstrated occlusion of the MCA artery was reviewed. Eight patients presented with a major disabling stroke and five of these died during the acute phase ...
D E, Moulin, R, Lo, J, Chiang, H J, Barnett   +3 more
openaire   +2 more sources