Results 161 to 170 of about 8,319,660 (396)

"Whither the Middle Class'? A Dynamic View" [PDF]

open access: yes
Research using cross-sectional survey 'snapshots' of household income taken over the past quarter century reveals a growing inequality in the distribution of annual money income of households in the United States (Thurow, 1987; Levy, 1987; Levy and ...
Greg J. Duncan   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Editorial - Erosion of the Middle Class?

open access: yessozialpolitik.ch, 2019
Monica Budowski, Sebastian Schief
doaj   +1 more source

Mitigating the identity and health threat of COVID-19: Perspectives of middle-class South Asians living in the UK. [PDF]

open access: yesJ Health Psychol, 2022
Hanson K   +4 more
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

HISTORIA Y POLÍTICA EN ARISTÓTELES: Constitución de Atenas y Política

open access: yesByzantion Nea Hellás, 2009
Esta exposición llama la atención sobre la vinculación estrecha que hay entre historia y política en la filosofía política aristotélica, así como mostrar que Aristóteles, metodológicamente, se sirvió de la investigación histórico-política para levantar ...
Héctor Eduardo García Cataldo
doaj  

Willingness to pay for an intervention that reduces soda consumption among a sample of middle-class adult Mexicans. [PDF]

open access: yesPLoS One, 2021
Colchero MA   +4 more
europepmc   +1 more source

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