Australia should focus on Asia’s millionaires – not its “middle class” [PDF]
Australia’s corporate strategists and national economic planners are mesmerised by what they believe will be rich pickings from the growth of Asia’s middle class.
Tejpavan Gandhok
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
THE ECONOMIC FACTORS AND CONSEQUENCES OF SOCIAL INEQUALITY AND POVERTY
Baltic Journal of Economic Studies, 2017 The purpose of the study is to determine the main factors and prerequisites for inequality and poverty of the population of Ukraine, as well as to identify the main consequences of this phenomenon and finding out of the main directions of the socio ...
Inessa Sytnik +2 more
doaj
Kratom Use in the US: Both a Regional Phenomenon and a White Middle-Class Phenomenon? Evidence From NSDUH 2019 and an Online Convenience Sample. [PDF]
Front Pharmacol, 2021 Rogers JM +3 more
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Gender and telework: Work and family experiences of teleworking professional, middle-class, married women with children during the Covid-19 pandemic in Turkey. [PDF]
Gend Work Organ, 2022 Çoban S.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Environmental Dynamics and Digital Transformation in Lower-Middle-Class Hospitals: Evidence from Indonesia. [PDF]
Healthcare (Basel)Binsar F +4 more
europepmc +1 more source
Parenting as a full time job: The experience of secular middle-class Jewish parents of transgender emerging adults in Israel. [PDF]
Int J Transgend Health, 2022 Nadan Y.
europepmc +1 more source