Results 201 to 210 of about 619,026 (264)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

On the Identification of the Middle Class [PDF]

open access: possible, 2013
The paper examines the identification of the “middle class” using data from LIS and LWS. It first considers definitions based purely on income, examining the rationale for different approaches and illustrating the implications for changes over time. It argues that the concept of “class” requires the examination of other dimensions beyond income.
Anthony B. Atkinson, Andrea Brandolini
openaire   +1 more source
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Middle classes

2017
This issue of the Caucasus Analytical Digest discusses Middle Classes in the South Caucasus; Yuliana Melkumyan gives a systematic overview of the main features of the middle class in Armenia based on their self-perception as captured in representative surveys; Alexi Gugushvili posits that ‘the middle class’ in the Georgian context is still largely in ...
Melkumyan, Yuliana   +2 more
openaire   +2 more sources

The Manifesto and the Middle Class

Critical Sociology, 2001
This paper examines Marx's claim in the Manifesto that capitalist society would polarize into two classes in light of the current evidence on growing inequality in American society. It argues that the middle class of industrial society is not an anomaly but a product of the incomplete development of capitalism and this middle class is presently being ...
openaire   +1 more source

The Middle Class

2022
This chapter analyzes the status of the middle class in America. It starts with defining the middle class; it continues with the danger of shrinking and tries to provide a mind genomics approach to middle-class problems. Analyzing the middle class in-depth is essential as it holds the key to the country's future.
openaire   +1 more source

On the Middle Class [PDF]

open access: possible, 2013
The Middle class as a concept has evolved over time, taking on various meanings at various points throughout history, becoming an object to aspire to for poor people, an object of desire for a strong government, a buzzword for politicians the world over, and the source of new customers for firms, and the global economy more broadly.
Michael MacLennan   +1 more
openaire   +2 more sources

The New Middle Class: I

1951
Abstract IN the early nineteenth century, although there are no exact figures, probably four-fifths of the occupied population were self-employed enterprisers; by 1870, only about one-third, and in 1940, only about one-fifth, were still in this old middle class.
openaire   +1 more source

The Middle Classes

2020
Abstract This chapter surveys the history of the middle classes in Weimar Germany from social, political, and cultural perspectives. Divisions—between industrialists and master artisans; conservatives, liberals, and left-wingers; Protestants, Catholics, and Jews; modernists and anti-modernists—were by no means new.
openaire   +2 more sources

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