Results 241 to 250 of about 3,096,700 (302)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
2017
This issue of the Caucasus Analytical Digest discusses Middle Classes in the South Caucasus; Yuliana Melkumyan gives a systematic overview of the main features of the middle class in Armenia based on their self-perception as captured in representative surveys; Alexi Gugushvili posits that ‘the middle class’ in the Georgian context is still largely in ...
Melkumyan, Yuliana +2 more
openaire +2 more sources
This issue of the Caucasus Analytical Digest discusses Middle Classes in the South Caucasus; Yuliana Melkumyan gives a systematic overview of the main features of the middle class in Armenia based on their self-perception as captured in representative surveys; Alexi Gugushvili posits that ‘the middle class’ in the Georgian context is still largely in ...
Melkumyan, Yuliana +2 more
openaire +2 more sources
2015
The analysis of strategies of class reproduction has become a key way of understanding the middle classes and different fractions of work, identity and lifestyle within them. It is the core of Bourdieu’s neo-Marxist sociology but is also crucial to more liberal, Weberian approaches concerned with social mobility (or the lack of it) (Goldthorpe, 1996 ...
Bridge, Gary, Fijalkow, Yankel
openaire +3 more sources
The analysis of strategies of class reproduction has become a key way of understanding the middle classes and different fractions of work, identity and lifestyle within them. It is the core of Bourdieu’s neo-Marxist sociology but is also crucial to more liberal, Weberian approaches concerned with social mobility (or the lack of it) (Goldthorpe, 1996 ...
Bridge, Gary, Fijalkow, Yankel
openaire +3 more sources
2012
Despite copious studies on the middle classes, there is no single, widely held definition of the middle class. Some scholars define the middle class in terms of the relation to the means of production, others in terms of relative incomes, and still others in terms of consumption patterns.
openaire +1 more source
Despite copious studies on the middle classes, there is no single, widely held definition of the middle class. Some scholars define the middle class in terms of the relation to the means of production, others in terms of relative incomes, and still others in terms of consumption patterns.
openaire +1 more source