Results 81 to 90 of about 589,671 (265)

The middle class: the mew convergence. Paradigm

open access: yesSociologie Românească, 2005
Throughout the modern world the middle class is increasingly looked upon as a precondition of stability in the social structures, as a means of softening social inequalities, as a way of retaining the status quo, as an instrument of achieving confidence ...
Nikolai Tilkidjiev
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Middle Class is Us: Measuring Indonesian Middle Class [PDF]

open access: yesProceedings of the 2nd International Conference on Indonesian Economy and Development (ICIED 2017), 2018
Turro S. Wongkaren, Ketut Krisna
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Construction d'enquête et définition des groupes sociaux

open access: yesSociologies, 2010
In this paper, we study Jerrold Seigel's book through the prism of the issue of the relation between the way the author constructs his object and that of the inquiry.
Cyprien Tasset
doaj  

The TG/HDL-c Lipid Ratio as a Cardiovascular Risk Marker in a Mexican Urban Middle-Class Population: Do We Need a Risk Score Tailored for Mexicans? [PDF]

open access: yesJ Clin Med, 2023
Martínez-Marroquín Y   +6 more
europepmc   +1 more source

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