Results 151 to 160 of about 2,602,328 (411)

Late onset middle ear neuroendocrine tumor presenting with distant metastasis

open access: yesOtolaryngology Case Reports, 2021
Tumors of the ear with neuroendocrine features are a very rare group of neoplasms, with neuroendocrine adenoma representing the more frequent entity found; the prevalence of middle ear neuroendocrine tumors is so low that it has never been determined ...
Federica Pollastri   +5 more
doaj  

Interaction of supernova blast waves with wind-driven shells: formation of "jets", "bullets", "ears", etc [PDF]

open access: yesOdessa Astron. Publ., 12 (1999) 117, 1999
Most of middle-aged supernova remnants (SNRs) have a distorted and complicated appearance which cannot be explained in the framework of the Sedov-Taylor model. We consider three typical examples of such SNRs (Vela SNR, MSH 15-52, G 309.2-00.6) and show that their structure could be explained as a result of interaction of a supernova (SN) blast wave ...
arxiv  

Hyperostotic tympanic bone spicules in domestic and wild animal species [PDF]

open access: yes, 2016
Hyperostotic tympanic bone spicules (HTBS), or "mucoperiosteal exostoses" (ME, syn.) are small, globular (>= 1 mm in diameter), mostly stalked and drumstick-like, bony structures, which arise from the inner wall of the tympanic bulla and project into the
Blutke, A   +5 more
core   +2 more sources

Polydopamine Nanohydrogel Decorated Adhesive and Responsive Hierarchical Microcarriers for Deafness Protection

open access: yesAdvanced Science, EarlyView.
A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen   +8 more
wiley   +1 more source

Missense MED12 variants in 22 males with intellectual disability: From nonspecific symptoms to complete syndromes

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 135-143, January 2023., 2023
Abstract We describe the phenotype of 22 male patients (20 probands) carrying a hemizygous missense variant in MED12. The phenotypic spectrum is very broad ranging from nonspecific intellectual disability (ID) to the three well‐known syndromes: Opitz–Kaveggia syndrome, Lujan–Fryns syndrome, or Ohdo syndrome.
Nuno Maia   +30 more
wiley   +1 more source

Inner ear disturbances related to middle ear inflammation [PDF]

open access: yes, 2017
2017-02The inner and middle ear are connected mainly through round and oval windows, and inflammation in the middle ear cavity can spread into the inner ear, which might induce a disturbance.
69453, Sone, Michihiko
core  

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

open access: yesAdvanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei   +18 more
wiley   +1 more source

Two SOX11 variants cause Coffin–Siris syndrome with a new feature of sensorineural hearing loss

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 183-189, January 2023., 2023
Abstract Coffin‐Siris syndrome (CSS, OMIM#135900) is a rare congenital disorder associated with neurodevelopmental and dysmorphic features. The primary cause of CSS is pathogenic variants in any of 9 BAF chromatin‐remodeling complex encoding genes or the genes SOX11 and PHF6. Herein, we performed whole‐exome sequencing (WES) and a series of analyses of
Qiuquan Wang   +5 more
wiley   +1 more source

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