Results 31 to 40 of about 150,816 (267)
Middle ear mucosal regeneration by tissue-engineered cell sheet transplantation
npj Regenerative Medicine, 2017 Nose tissue that helps the ear heal Transplanting a sheet of cells from the nose to the middle ear could improve postoperative prognosis for middle ear inflammatory conditions.
Kazuhisa Yamamoto +7 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Review of otitis media microbiome studies: What do they tell us?
Laryngoscope Investigative Otolaryngology, 2020 Objectives To provide a state of the art review on accruing studies focused on defining the middle ear microbiome, highlighting the relationship of the microbiome to disease pathophysiology.
Juan Carlos Nogues +2 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Middle ear volume of middle ear diseases.
Practica Oto-Rhino-Laryngologica, 1986 A volumetric method (Boyle's law) was used to measure the middle ear volumes of 104 patients with middle ear diseases.Regression lines between middle ear volumes and X-ray middle ear areas were caliculated (y=0.93x-0.92) in eight cases of traumatic eardrum perforation.Average middle ear volumes were 12.00cc in traumatic eardrum perforations, 7.48cc in ...
Haruo TAKAHASHI +3 more
openaire +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Acta Acustica, 2022 Wideband acoustic immitance (WAI) measurements provide an objective means to detect pathological middle ear conditions. However, for ears of young infants, it is still difficult to make clear statements about the middle ear status based on WAI ...
Sankowsky-Rothe Tobias +2 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick +6 more
wiley +1 more source
Journal of Nepal Medical Association, 2022 Introduction: Middle ear barotrauma is a tissue injury to the ear secondary to inadequate pressure equalisation between the middle ear and the external environment. Paragliding, though an exciting sport, has its own risks and hazards.
Biraj Baral +3 more
doaj +1 more source