Results 31 to 40 of about 160,956 (317)

Inner Ear Therapeutics: An Overview of Middle Ear Delivery

Frontiers in Cellular Neuroscience, 2019
There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel, Mikhaylo Szczupak, Suhrud Rajguru, Suhrud Rajguru, Carey Balaban, Michael E. Hoffer, Michael E. Hoffer   +6 more
doaj   +1 more source

Diagnostic Performance of Endoscopic and Microscopic Procedures for Identifying Different Middle Ear Structures and Remaining Disease in Patients with Chronic Otitis Media: A Prospective Cohort Study. [PDF]

PLoS ONE, 2015
BACKGROUND:The diagnostic performance of endoscopic and microscopic procedures for detecting diseases of the middle ear in patients with chronic otitis media (COM) has rarely been investigated. This study was conducted to compare the performance of these
Farhad Farahani, Elnaz Shariatpanahi, Javane Jahanshahi, Jalal Poorolajal   +3 more
doaj   +1 more source

Middle ear mucosal regeneration by tissue-engineered cell sheet transplantation

npj Regenerative Medicine, 2017
Nose tissue that helps the ear heal Transplanting a sheet of cells from the nose to the middle ear could improve postoperative prognosis for middle ear inflammatory conditions.
Kazuhisa Yamamoto, Masayuki Yamato, Tsunetaro Morino, Hiroaki Sugiyama, Ryo Takagi, Yuichiro Yaguchi, Teruo Okano, Hiromi Kojima   +7 more
doaj   +1 more source

Review of otitis media microbiome studies: What do they tell us?

Laryngoscope Investigative Otolaryngology, 2020
Objectives To provide a state of the art review on accruing studies focused on defining the middle ear microbiome, highlighting the relationship of the microbiome to disease pathophysiology.
Juan Carlos Nogues, Marcos Pérez‐Losada, Diego Preciado   +2 more
doaj   +1 more source

THE PHYSIOLOGY OF THE MIDDLE EAR. [PDF]

JAMA: The Journal of the American Medical Association, 1904
The scope of this paper embraces the following parts: 1, the drum cavity; 2, the attic; 3, the aditus ad antrum; 4, the mastoid antrum; 5, the mastoid cells; 6, the eustachian tube. The function of the eustachian tube is, first, to ventilate the middle ear, and secondly, to drain the secretions from the middle ear into the nasopharynx.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Parametric model of young infants’ eardrum and ear canal impedances supporting immittance measurement results. Part I: Development of the model

Acta Acustica, 2022
Wideband acoustic immitance (WAI) measurements provide an objective means to detect pathological middle ear conditions. However, for ears of young infants, it is still difficult to make clear statements about the middle ear status based on WAI ...
Sankowsky-Rothe Tobias, van de Par Steven, Blau Matthias   +2 more
doaj   +1 more source

A Multi‐Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano, Denis Balaban, Yihan Zhang, Brian Healy, Bart K. Chwalisz, Michael Levy, Nagagopal Venna, Barney J. Stern, Carlos A. Pardo, Paula Barreras, Nicole Bou Rjeily, Eoin P. Flanagan, Vyanka Redenbaugh, Allen J. Aksamit Jr., Spencer Hutto, Max Herman, Sally El Sammak, Elsa C. Rodriguez, Laura Snider, Hannah Rains, Mayra Montalvo, Torge Rempe, Sergi Martinez Ramirez, Lucas Horta, Stacey Clardy, Jennifer Lord, Tracey A. Cho, Lama Abdel Wahed, Joseph R. Berger, Rohini D. Samudralwar, Noellie Rivera Torres, David B. Clifford, Steven Richard Dunham, Masoud Majed, Aram Zabeti, Samuel Marcucci, Yang Mao‐Draayer, Jon Doty, Paunel B. Agyei, Shamik Bhattacharyya   +39 more
wiley   +1 more source

Middle Ear Barotrauma among Licensed Para-pilots of a Metropolitan City: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: Middle ear barotrauma is a tissue injury to the ear secondary to inadequate pressure equalisation between the middle ear and the external environment. Paragliding, though an exciting sport, has its own risks and hazards.
Biraj Baral, Deepak Regmi, Aakriti Dawadi, Bibek Adhikari   +3 more
doaj   +1 more source