Results 71 to 80 of about 155,773 (264)

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Ear endoscopic Surgery: Dissection of the Middle Ear

International Archives of Otorhinolaryngology, 2009
Introdução: Endoscópios são equipamentos utilizados com sucesso em diversos procedimentos de várias especialidades médicas. Entretanto, na área da otologia, mesmo com a incorporação dos endoscópios em procedimentos conjuntos com microscópio, os ...
Nogueira Júnior, João Flávio, Cruz, Daniel Nogueira   +1 more
doaj  

Maskless Fabrication of PLA‐Based Neural Arrays for CNS Recording and Stimulation

Advanced Materials Interfaces, EarlyView.
Biodegradable neural interfaces enable bidirectional communication with the CNS. Through electrochemical characterization, ageing tests with impedance monitoring, and in vivo validation, we assess the performance of PLA‐based epicortical and spinal implants.
Anna De Salvo, Federica Velluto, Ilenia Sergi, Michele Di Lauro, Verónica Barranco‐Maresca, Elena Alonso‐Calviño, Yasmina Hernández‐Martín, Juan Aguilar, Juliana M. Rosa, María C. Serrano, Carolina Giulia Ferroni, Federico Rondelli, Elisa López‐Dolado, Luciano Fadiga, Fabio Biscarini   +14 more
wiley   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

Advanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib, Tim‐Joshua Strauß, Jennifer Harre, Madeleine Goblet, Florian Klodwig‐Kirstein, Jana Schwieger, Michaela Kreienmeyer, Verena Scheper, Athanasia Warnecke, Nina Ehlert, Peter Behrens   +10 more
wiley   +1 more source

Erosion of the incus by the chorda tympani nerve in a normally ventilated middle ear and its implications during stapedotomy

Otolaryngology Case Reports, 2017
A case is reported showing partial erosion of the incus long process by the chorda tympani nerve in a normally ventilated middle ear: type A tympanogram, no tympanic membrane retraction, normal middle ear mucosa.
Frédéric Lemieux-Martel, Margaret Aron, MDCM, FRCSC   +1 more
doaj   +1 more source

Middle Ear Adenoma

Archives of Pathology & Laboratory Medicine, 2006
Abstract Middle ear adenoma is a benign tumor of the middle ear that can have exocrine (mucinous) and/or neuroendocrine differentiation. Early authors described a separate tumor with predominantly neuroendocrine differentiation as a middle ear carcinoid tumor, but these are now known to be the same tumor. We review the literature of this
Stephen, Berns, Gary, Pearl
openaire   +2 more sources

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

Advanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo, Shanshan Jiang, Yimian Luo, Adele Moatti, Farnaz Matin‐Mann   +4 more
wiley   +1 more source

Fabrication of Fibers With Complex Features Using Thermal Drawing of 3D‐Printed Preforms

Advanced Materials Technologies, EarlyView.
3D printing enables rapid fabrication of macroscale polymer preforms with complex geometries. Thermal drawing then scales these structures into long fibers while preserving micron‐scale cross‐sectional features. This workflow provides a fast, low‐cost route to functional fibers with tailored geometries and material combinations for catheter, robotic ...
Ali Anil Demircali, Jinshi Zhao, Ayhan Aktas, Mohamed E. M. K. Abdelaziz, Burak Temelkuran   +4 more
wiley   +1 more source

Middle Ear Papilloma

Brazilian Journal of Otorhinolaryngology, 2007
Papillomas are benign, however locally invasive tumors normally originated in the larynx and nasosinusal tract. These tumors can be described from their specific histological and morphologic characteristics. Recurrence is common if excision is inadequately performed.
de Menezes Santos Torres, Sandro, Castro, Thomas Wagner, Bento, Ricardo Ferreira, Lessa, Hélio Andrade   +3 more
openaire   +2 more sources