Epidermal Growth Factor Expression in Middle Ear Cholesteatoma [PDF]
Kaohsiung Journal of Medical Sciences, 2004 Middle ear cholesteatoma is destructive to auditory ossicles and temporal bone, and treatment usually requires surgical removal of all epithelial content.
Kuen-Yao Ho, Ka-wo Lee, Chee-Yin Chai
exaly +5 more sources
Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing. [PDF]
BMC Med GenomicsBackground The present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles in its pathogenesis.
Xie M +9 more
europepmc +3 more sources
Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma. [PDF]
Front Genet, 2023 Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Xie S +6 more
europepmc +2 more sources
N6-methyladenosine methylation analysis of circRNAs in acquired middle ear cholesteatoma. [PDF]
Front GenetIntroductionMiddle ear cholesteatoma is a chronic middle ear disease characterized by severe hearing loss and adjacent bone erosion, resulting in numerous complications.
He J +5 more
europepmc +2 more sources
Middle ear cholesteatoma in two cats diagnosed with the aid of video-otoscopy. [PDF]
JFMS Open Rep, 2023 Case series summary The present report describes middle ear cholesteatoma in two cats and also the use of video-otoscopy and flushing to assist with the diagnosis.
Botelho CB +5 more
europepmc +2 more sources
Immunohistochemical localization of d-β-aspartic acid in congenital and acquired middle ear cholesteatoma. [PDF]
Laryngoscope Investig Otolaryngol, 2022 Objective/Hypothesis Middle ear cholesteatoma is characterized by abnormal growth of the keratinizing squamous epithelium of the temporal bone. d‐β‐aspartic acid is the major isomer of d‐aspartic acid found in elderly tissue.
Kitaya S +12 more
europepmc +2 more sources
Microarray analysis and functional prediction of differentially expressed circular RNAs in acquired middle ear cholesteatoma. [PDF]
Biomed Eng Online, 2021 Background Middle ear cholesteatoma is characterized by hyper-proliferation of keratinocytes. Circular RNA (circRNA) plays an essential role in the pathogenesis of many proliferative diseases.
Xie S, Jin L, Yin T, Ren J, Liu W.
europepmc +2 more sources
Expression of tumor necrosis factor alpha, interleukin-1 and matrix metalloproteinase-9 and pathomorphological changes in acquired middle ear cholesteatoma [PDF]
Biomedicinska istraživanja, 2021 Introduction. The inflammatory mediators play a central role in the pathogenesis of the inflammatory process of the middle ear and cholesteatoma from the aspect of initiating and maintaining the inflammatory response to infection and lesion.
Dalibor Vranješ +2 more
doaj +1 more source
Philippine Journal of Otolaryngology Head and Neck Surgery, 2021 Objective: To determine the stage of middle ear cholesteatoma of patients who underwent middle ear surgery at the Southern Philippines Medical Center from January to December 2019, based on European Academy of Otology and Neurotology / Japan ...
Dominador Toral, Chris Robinson Laganao
doaj +1 more source
Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear [PDF]
Clinical and Experimental Otorhinolaryngology, 2023 Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimated that over five million people around the world have suffered from middle ear cholesteatoma.
Dongliang Liu +3 more
doaj +1 more source