Results 41 to 50 of about 11,404 (251)

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Simulation Platform for Myringotomy with Ventilation Tube Insertion in Adult Ears

Philippine Journal of Otolaryngology Head and Neck Surgery, 2018
Objective: To develop a ventilation tube insertion simulator for training and evaluation of otorhinolaryngology residents in myringotomy with ventilating tube insertion. Methods:             Design:            Cross - Sectional Study            
Abner L. Chan, Ryner Jose D. Carrillo, Kimberly C. Ong   +2 more
doaj   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall, Abbas I. Hussain, Michelle Cho, Patrick A. Forcelli   +3 more
wiley   +1 more source

The effect of intervelar veloplasty under magnification (Sommerlad’s Technique) without tympanostomy on middle ear effusion in cleft palate patients

BMC Pediatrics, 2021
Objective Different surgical techniques and management approaches have been introduced to manage the cleft palate (CP) and its complications, such as otitis media with effusion (OME) and auditory problems.
Mohammad Ali Hoghoughi, Tayebeh Kazemi, Ali Khojasteh, Raha Habibagahi, Zahra Kalkate, Zeynab Zarei, Hamidreza Hosseinpour, Maryam Salimi   +7 more
doaj   +1 more source

Effect of epileptogenesis on hypercapnic cardioventilatory response in kainic acid rats

Epilepsia, EarlyView.
Abstract Objective Cardioventilatory failure is the leading mechanism proposed to underlie sudden unexpected death in epilepsy (SUDEP), which occurs predominantly at night in patients with generalized tonic–clonic seizures. Interictal hypercapnic cardioventilatory responses are suggested to be involved, as they are ablated in chronically epileptic ...
Auriane Apaire, Elise Collard, Abigail Niyibizi, Natasha N. Kumar, Enrique Germany Morrison, Javier Chavez Cerda, Ayse S. Dereli, Riem El Tahry   +7 more
wiley   +1 more source

The Efficacy of Transcanal Endoscopic Ear Surgery in Children Compared to Adults

Children
Background/Objectives: Using transcanal endoscopic ear surgery to manage middle ear disease in children remains a controversial topic. The aim of this study was to compare the efficacy of transcanal endoscopic ear surgery between children and adults ...
Wan-Hsuan Sun, Chia-Ho Chen, Chao-Yin Kuo, Sheng-Yao Cheng, Tzu-Chin Huang   +4 more
doaj   +1 more source

Interventions for adult Eustachian tube dysfunction: asystematic review

Health Technology Assessment, 2014
Background: Eustachian tube dysfunction (ETD) is the inability of the Eustachian tube (ET) to adequately perform at least one of its functions: to protect the middle ear from sources of disease, to ventilate the middle ear, and to help drain secretions ...
Alexis Llewellyn, Gill Norman, Melissa Harden, Andrew Coatesworth, Daniel Kimberling, Anne Schilder, Catriona McDaid   +6 more
doaj   +1 more source

Endoscopic ear surgery: then and now, review article

The Egyptian Journal of Otolaryngology, 2022
Objective Endoscopic ear surgery (EES) is a growing and well-recognized field in the modern era. EES had a stepwise journey of development. This journey is pretty comparable to the endoscopic sinus surgery development.
Waleed Moneir, Mohamed Elkahwagi
doaj   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source

Importance of early ventilation tubes insertion in chronic otitis media with effusion in children with congenital cleft palate [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Otitis media with effusion (OME) is almost universal in children with cleft palate with an incidence of more than 90%, but the approach to managing this problem varies significantly among authors.
Šubarević Vladan, Arsović Nenad, Simić Radoje, Stanković Katarina   +3 more
doaj   +1 more source