Results 51 to 60 of about 127,062 (232)

Emergence of the Middle East Respiratory Syndrome Coronavirus

PLoS Pathogens, 2013
It began routinely enough. A patient with severe respiratory disease at the Dr. Soliman Fakeeh Hospital in Jeddah, Saudi Arabia was getting worse and no one knew why. A sample of sputum was sent to Dr. Ali Mohamed Zaki to identify the culprit, as he had identified these diseases many times before. However, this time would be different.
Christopher M. Coleman, Matthew B. Frieman   +1 more
openaire   +5 more sources

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

Developmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel, Maya Silver, Aaron H. Wasserman, Samantha Rea, Charles C. Hong, Charles H. Williams   +5 more
wiley   +1 more source

Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012 [PDF]

, 2012
Coronaviruses have the potential to cause severe transmissible human disease, as demonstrated by the severe acute respiratory syndrome (SARS) outbreak of 2003.
Aarons, E., Bermingham, A. (Alison), Boddington, N.L., Brown, C.S., Brown, K.E. (Kevin), Chand, M.A., Drosten, C. (Christian), Fouchier, R.A.M. (Ron), Galiano, M. (Monica), Gopal, R. (Robin), Green, H.K., Hoschler, K., Langrish, C., Myers, R.H. (Richard), Newsholme, W., Pebody, R.G., Price, N., Tong, C., Zambon, M.C. (Maria)   +18 more
core  

The impact of co-infection of influenza A virus on the severity of Middle East Respiratory Syndrome Coronavirus [PDF]

, 2017
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Alfaraj, Sarah H., Altwaijri, Talal A., Alzahrani, Nojoom A., Memish, Ziad A.   +4 more
core   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source

Hematologic, hepatic, and renal function changes in hospitalized patients with Middle East respiratory syndrome coronavirus [PDF]

, 2017
Background There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS‐CoV) infection. Methods This is a retrospective cohort study of 16 MERS‐
Abbasi, S., Al-Tawfiq, J. A., Babiker, M., Eltigani, M., Hinedi, K., Sunji, A.   +5 more
core   +1 more source

Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus [PDF]

New England Journal of Medicine, 2013
In September 2012, the World Health Organization reported the first cases of pneumonia caused by the novel Middle East respiratory syndrome coronavirus (MERS-CoV). We describe a cluster of health care-acquired MERS-CoV infections.Medical records were reviewed for clinical and demographic information and determination of potential contacts and exposures.
Abdulmohsen Almulhim, Jaffar A. Al-Tawfiq, Rafat F. Alhakeem, Abdullah M. Assiri, Simon J. Watson, Alimuddin Zumla, Alimuddin Zumla, Allison McGeer, Ziad A. Memish, Hossam Madani, Derek A. T. Cummings, Trish M. Perl, Hatem Q. Makhdoom, Abdullah A. Al Rabeeah, Connie S. Price, Paul Kellam, Paul Kellam, Matthew Cotten, Zaki N. Alabdullatif, Maher Assad   +19 more
openaire   +2 more sources

Phytochemical Contents and Bioactive Compounds in Widely Consumed Cereals, Legumes, and Vegetables in Abruzzo Region, Italy: A Critical Review

Food Safety and Health, EarlyView.
This review aims to collect and identify cereals, legumes, and vegetables mostly consumed in the Abruzzo region from 2020 till now, pointing attention to their biological effects. ABSTRACT The Abruzzo region boasts a wide range of typical food products including cereals, legumes, and vegetables. In this context, they take part in the Mediterranean diet,
Giulia Gentile, Lorenza Marinaccio, Adriano Mollica, Azzurra Stefanucci   +3 more
wiley   +1 more source

Middle East respiratory syndrome [PDF]

Intensive Care Medicine, 2014
Charles D. Gomersall, Chi Hung Czarina Leung   +1 more
openaire   +4 more sources

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia [PDF]

, 2018
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Alfaraj, Sarah H., Altuwaijri, Talal A., Memish, Ziad A.   +3 more
core   +1 more source