Results 81 to 90 of about 161,060 (284)

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East

Viruses, 2019
Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries then exported into Africa and Middle East for consumption. To understand the distribution of MERS-
Ahmed Kandeil, Mokhtar Gomaa, Ahmed Nageh, Mahmoud M. Shehata, Ahmed E. Kayed, Jamal S. M. Sabir, Awatef Abiadh, Jamel Jrijer, Zuhair Amr, Mounir Abi Said, Denis K. Byarugaba, Fred Wabwire-Mangen, Titus Tugume, Nadira S. Mohamed, Roba Attar, Sabah M. Hassan, Sabah Abdulaziz Linjawi, Yassmin Moatassim, Omnia Kutkat, Sara Mahmoud, Ola Bagato, Noura M. Abo Shama, Rabeh El-Shesheny, Ahmed Mostafa, Ranawaka A. P. M. Perera, Daniel K. W. Chu, Nagla Hassan, Basma Elsokary, Ahmed Saad, Heba Sobhy, Ihab El Masry, Pamela P. McKenzie, Richard J. Webby, Malik Peiris, Yilma J. Makonnen, Mohamed A. Ali, Ghazi Kayali   +36 more
doaj   +1 more source

Covid-19 and its impacts on consumer decision-making process [PDF]

, 2015
The term "virus" derives from the Latin word for "venom" and refers to a microscopic infectious agent. On the other hand, "corona" is named by its shape to look like a crown ring – the scientists who coined the word coronavirus in 1968 reasoned that ...
Harun, Amran, Hashim, Norashuha, Hasim, Muhammad Asyraf   +2 more
core  

The Middle East Respiratory Syndrome (MERS)

Infectious Disease Clinics of North America, 2019
The Middle East respiratory syndrome (MERS) is a novel lethal zoonotic disease of humans caused by the MERS coronavirus (MERS-CoV). Although MERS is endemic to the Middle East, travelers have exported MERS-CoV on return to their home countries. Clinical manifestations range from mild to severe acute respiratory disease and death.
Azhar, EI, Hui, DSC, Memish, ZA, Drosten, C, Zumla, A   +4 more
openaire   +3 more sources

Vaccine Development Against Middle East Respiratory Syndrome [PDF]

Current Tropical Medicine Reports, 2016
Various types of vaccines are under pre-clinical and clinical development to address the recent appearance of Middle East respiratory syndrome or MERS, an emerging infectious disease that has already caused over 600 deaths and remains a threat to world health.
Lee, Hai Yen, Nyon, Mun Peak, Strych, Ulrich   +2 more
openaire   +2 more sources

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

Advanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source

Middle East respiratory syndrome [PDF]

Intensive Care Medicine, 2014
Leung, Chi Hung Czarina, Gomersall, Charles David   +1 more
openaire   +3 more sources

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +8 more sources

Pathogenesis of Middle East respiratory syndrome coronavirus [PDF]

The Journal of Pathology, 2014
AbstractHuman coronaviruses (CoVs) mostly cause a common cold that is mild and self‐limiting. Zoonotic transmission of CoVs such as the recently identified Middle East respiratory syndrome (MERS)‐CoV and severe acute respiratory syndrome (SARS)‐CoV, on the other hand, may be associated with severe lower respiratory tract infection. This article reviews
van den Brand, Judith M A, Smits, Saskia L., Haagmans, Bart L   +2 more
openaire   +4 more sources

Exploring the Vasculitis‐Tumors Link: Epidemiological Patterns, Mechanistic Insights, and Clinical Implications

Advanced Science, EarlyView.
This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi, Zhijiao Li, Xin Ma, Bei Zhang, Xinfeng Wu, Hua Fan, Rongzeng Liu, Hongwei Jiang, Cong‐Qiu Chu   +8 more
wiley   +1 more source