Results 171 to 180 of about 93,615 (327)

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells

Journal of Biological Chemistry, 2018
Coronavirus tropism is predominantly determined by the interaction between coronavirus spikes and the host receptors. In this regard, coronaviruses have evolved a complicated receptor-recognition system through their spike proteins.
Hin Chu, C. Chan, Xi Zhang, Yixin Wang, Shuofeng Yuan, Jie Zhou, R. Au-Yeung, K. Sze, Dong Yang, H. Shuai, Yuxin Hou, Cun Li, Xiaoyu Zhao, V. Poon, S. Leung, M. Yeung, Jinghua Yan, G. Lu, D. Jin, G. Gao, J. Chan, K. Yuen   +21 more
semanticscholar   +1 more source

Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin

Antiviral Research, 2016
Highly pathogenic human coronaviruses associated with a severe respiratory syndrome, including Middle East respiratory syndrome coronavirus (MERS-CoV), have recently emerged. The MERS-CoV epidemic started in 2012 and is still ongoing, with a mortality rate of approximately 35%.
Jean K. Millet, Karin Séron, Rachael N. Labitt, Adeline Danneels, Kenneth E. Palmer, Gary R. Whittaker, Jean Dubuisson, Sandrine Belouzard   +7 more
openaire   +6 more sources

A decision support system for risk reduction in pandemic spread based on the management of passenger air traffic

International Transactions in Operational Research, Volume 32, Issue 4, Page 1893-1917, July 2025.
Abstract A significant factor in the early spread of pandemics at an international level is passenger air traffic. Decisions regarding passenger air traffic could assist different countries in managing the risk of pandemic importation. However, flight cancelations would have economic and social impacts, leading to a multiobjective optimization problem.
Gabriel A. Peña, Alfonso Mateos, Antonio Jiménez‐Martín, Raúl G. Sanchis   +3 more
wiley   +1 more source

Hematologic, hepatic, and renal function changes in hospitalized patients with Middle East respiratory syndrome coronavirus [PDF]

, 2017
Background There are no longitudinal data on the changes in hematologic, hepatic, and renal function findings in patients with Middle East respiratory syndrome coronavirus (MERS‐CoV) infection. Methods This is a retrospective cohort study of 16 MERS‐
Abbasi, S., Al-Tawfiq, J. A., Babiker, M., Eltigani, M., Hinedi, K., Sunji, A.   +5 more
core   +1 more source

A hydrophobic-interaction-based mechanism trigger docking between the SARS CoV 2 spike and angiotensin-converting enzyme 2 [PDF]

arXiv, 2020
A recent experimental study found that the binding affinity between the cellular receptor human angiotensin converting enzyme 2 (ACE2) and receptor-binding domain (RBD) in spike (S) protein of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is more than 10-fold higher than that of the original severe acute respiratory syndrome ...
arxiv  

A novel genotyping system based on site polymorphism on spike gene reveals the evolutionary pathway of porcine epidemic diarrhea virus

iMetaOmics, Volume 2, Issue 2, June 2025.
This study focuses on porcine epidemic diarrhea virus (PEDV), a highly virulent and rapidly evolving coronavirus threatening global swine production. We established a novel genotype system of PEDV targeting site‐specific polymorphisms in the spike (S) protein.
Mingkai Lei, Huimin Li, Xiaoyu Chen, Xiaozhen Li, Xuexiang Yu, Shengnan Ruan, Hao Wu, Ahmed H. Ghonaim, Ziyang Yan, Wentao Li, Qigai He   +10 more
wiley   +1 more source

Animal models of Middle East respiratory syndrome coronavirus infection

Antiviral Research, 2015
The emergence of the Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second time that a new, highly pathogenic coronavirus has emerged in the human population in the 21st century. In this review, we discuss the current state of knowledge of animal models of MERS-CoV infection.
van Doremalen, Neeltje, Munster, Vincent J.   +1 more
openaire   +4 more sources

Genetic and Inflammatory Signatures Associated With Worse Prognosis in Hospitalized Patients With Severe SARS‐CoV‐2 Infection With and Without Diabetes

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SAR‐CoV‐2) presents with a diverse symptomology, ranging from asymptomatic to severe disease, but the mechanism of risk factors such as diabetes remains unelucidated. The current retrospective cohort study of 182 patients, with and without COVID‐19 and diabetes, analyzed leftover blood specimens
Marshall Yuan, Andrew Wassef, Davit Sargsyan, Vahe Nersisyan, Javier Cabrera, Ronald G. Nahass, Wael Hassan, Ah‐Ng Kong, Luigi Brunetti   +8 more
wiley   +1 more source

MERS-CoV in Arabian camels in Africa and Central Asia [PDF]

, 2017
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causing infections in humans is genetically indistinguishable from the virus found in Arabian camels (dromedaries) in the Middle East. Although no primary human case of MERS was reported outside the
Chan, Samuel M.S., Chevalier, Véronique, Chu, Daniel K.W., Miguel, Eve, Peiris, Malik, Perera, Ranawaka A.P.M., Poon, Leo L.M., Roger, François   +7 more
core   +1 more source

Immune Responses to Middle East Respiratory Syndrome Coronavirus During the Acute and Convalescent Phases of Human Infection

Clinical Infectious Diseases, 2018
Background An understanding of immune responses against the Middle East respiratory syndrome (MERS) is important for the development of treatments and preventive measures.
Hyoung-Shik Shin, Yeonjae Kim, Gayeon Kim, Ji Yeon Lee, Ina Jeong, J. Joh, Hana Kim, Eunjin Chang, S. Y. Sim, Jun-Sun Park, D. Lim   +10 more
semanticscholar   +1 more source