Derivatives of MOPS: promising scaffolds for SARS coronaviruses Macro domain‐targeted inhibition
The SARS‐CoV/CoV‐2 genome encodes non‐structural protein 3, which contains a ‘Macro domain’. This protein domain exhibits antagonistic activity against interferon signaling, which disrupts the host innate immune response and can thus mediate viral escape, highlighting its therapeutic potential.
Oney Ortega Granda+5 more
wiley +1 more source
Unraveling the mysteries of Middle East respiratory syndrome coronavirus [PDF]
Dr. Aron Hall, a CDC coronavirus epidemiologist, discusses Middle East Respiratory Syndrome Coronavirus."I\ue2\u20ac\u2122m Dr. Aron Hall, for Emerging Infectious Diseases, and I\ue2\u20ac\u2122ve been reading my co-authored commentary, Unraveling the ...
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In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection [PDF]
Isabella Eckerle+4 more
openalex +1 more source
Vaccine against Middle East respiratory syndrome coronavirus [PDF]
Alimuddin Zumla+3 more
openaire +5 more sources
ABSTRACT Introduction Long Covid, the patient‐preferred term, describes symptoms persisting after an acute Covid‐19 infection. Understanding the importance and meaning of a Long Covid diagnosis to children and young people (CYP), their families and professionals associated with their care can give insight into the way that these diagnoses are used ...
Alice Faux‐Nightingale+6 more
wiley +1 more source
ABSTRACT Aim High‐impact infectious diseases pose major global health challenges, underscoring the urgent need for robust public health preparedness. Despite efforts to improve global health security, recent pandemics have revealed significant weaknesses in health systems’ preparedness and response capabilities.
KM Saif‐Ur‐Rahman+9 more
wiley +1 more source
Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description [PDF]
Mohammad Alabdallat+43 more
openalex +1 more source
The Middle East respiratory syndrome coronavirus
Jordi Reina, Núria Reina
openaire +4 more sources
Stochastic COVID‐19 epidemic model incorporating asymptomatic and isolated compartments
This study delves into the intricate dynamics of the COVID‐19 epidemic by extending a deterministic compartmental model incorporating asymptomatic, quarantined and isolated compartments, with a stochastic model capturing the natural randomness of the processes.
Tomás Caraballo+5 more
wiley +1 more source
Middle East Respiratory Syndrome Coronavirus: A Case-Control Study of Hospitalized Patients [PDF]
Jaffar A. Al‐Tawfiq+6 more
openalex +1 more source