Results 121 to 130 of about 10,555 (249)

High‐Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair

Advanced Science, EarlyView.
A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Apresio K. Fajrial, Leyla Akh, Stephanie E. Schneider, Wei Tan, Corey P. Neu, Xiaoyun Ding   +5 more
wiley   +1 more source

Synthetic data Using Population Profiles for cardiOvascular Risk facTors (SUPPORT) in mainland China. [PDF]

Sci Data
Liu Q, Guo Y, Lu M, Zhou Y, Gao X, Tang X, Gao P.   +6 more
europepmc   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Plant Chemistry and Enemy Pressure Shape Within-Stem Distribution of the Invasive Scale Nipponaclerda biwakoensis. [PDF]

Insects
Glassmire AE, Cronin JT, Diaz R, DeSoto A, Shapiro E, Gaffke A, Snook JS, Stout M.   +7 more
europepmc   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Hidden in the pollen: tracing 3000 years of human footprints in a mountain landscape. [PDF]

Sci Rep
Jamrichová E, Benediková L, Petr L, Barta P, Hajnalová M.   +4 more
europepmc   +1 more source

Current Challenges of Transcription Compartmentalization Research

Advanced Science, EarlyView.
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley   +1 more source

The Old Lady spider cave skeletons in Ladakh have diverse maternal genetic origin. [PDF]

iScience
Kumar L, Rajpal R, Dwivedi A, Kumar P, Pasupuleti N, Kumar S, Spalzin S, Rabyang S, Rai N.   +8 more
europepmc   +1 more source

Substrate Engineering of SWCNT p–n Junctions for Dual‐Mode Power Generation and Heat‐Flux Sensing

Advanced Science, EarlyView.
Through substrate engineering alone, a single‐walled carbon nanotube p–n junction device switches between two functions under uniform infrared irradiation. A low‐absorbance substrate sustains a central hot junction for continuous power generation, whereas high‐absorbance substrates transiently invert the temperature gradient for sensitive heat‐flux ...
Ryota Tamai, Hiroto Nakayama, Shuya Ochiai, Masayuki Takashiri   +3 more
wiley   +1 more source

Settlement heritage on the Coastal Peninsula: an investigation of the spatiotemporal evolution of Shandong Province via GIS. [PDF]

Sci Rep
Pan Z, Huang Y, Guo Q, Qin Y, Deng Q, Liang J, Zheng L, Chen Y.   +7 more
europepmc   +1 more source