Results 21 to 30 of about 3,787,785 (297)
Pasture names with Romance and Slavic roots facilitate dissection of Y chromosome variation in an exclusively German-speaking alpine region. [PDF]
The small alpine district of East Tyrol (Austria) has an exceptional demographic history. It was contemporaneously inhabited by members of the Romance, the Slavic and the Germanic language groups for centuries.
Harald Niederstätter +10 more
doaj +1 more source
The Rubik Cube of the Wider Middle East. CEPS Paperback. February 2003 [PDF]
Given the complexity and severity of the problems involved, this book asserts that a comprehensive regional initiative for the Wider Middle East is called for and proceeds to outline exactly what that would entail.
Emerson, Michael, Tocci, Nathalie
core
Çin'in Körfez'deki Enerji Güvenliği
China became the world's largest net oil importer in 2013; half of this oil comes from the Middle East, and about 30% comes from the Gulf countries. Despite efforts to diversify its energy use, China is expected to import more oil from the Middle East ...
Yoncacı, Alperen
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
OSU Middle East Studies Bulletin
A Biannual Publication of the Middle East Studies ...
Ohio State University. Middle East Studies Center
core +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The International Aspect of the Establishment of the State of Palestine
From the very beginning of the Middle East conflict the relations between the Israelis and the Palestinians as well as the problem of establishing a Palestinian state have gone far beyond the region to become an issue of the international political ...
Avad. Zaully
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source

