Results 111 to 120 of about 310,651 (299)

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Language and migration : the impact of the Jukun on Chadic speaking groups in the Benue-Gongola basin [PDF]

, 2006
Our paper deals with the problems of migration, culture and language in the wider Benue-Gongola basin. Here are mainly concerned the West-Chadic speaking groups Kwami, Kupto, Kushi and Piya as well as the Jukun who speak a language belonging to the Benue-
Dinslage, Sabine, Leger, Rudolf
core  

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen, Anna‐Maija Tolppanen, Valtteri Kaasinen, Marjaana Koponen, Sirpa Hartikainen   +4 more
wiley   +1 more source

Artificial Intelligence for Text Analysis in the Arabic and Related Middle Eastern Languages: Progress, Trends, and Future Recommendations

International Journal of Intelligent Systems
In the last 10 years, there has been a rise in the number of Arabic texts, which necessitates a more profound understanding of algorithms to efficiently understand and classify Arabic texts in many applications, like sentiment analysis. This paper presents a comprehensive review of recent developments in Arabic text classification (ATC) and Arabic text
Abdullah Y. Muaad, Md Belal Bin Heyat, Faijan Akhtar, Usman Naseem, Wadeea R. Naji, Suresha Mallappa, Hanumanthappa J.   +6 more
openaire   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

ACKR1/Duffy‐null genotype testing for clozapine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Abstract Clozapine is licenced for treatment‐resistant schizophrenia and psychosis in Parkinson's disease. In the United Kingdom, there is a mandatory requirement for absolute neutrophil count (ANC) and white blood cell count (WBC) monitoring to safeguard against agranulocytosis.
Stephen Murtough, Oriella Stellakis, Daisy Mills, Blanca Bjourson, Vicky Chaplin, Dharmisha Chauhan, Bev Chipp, Marius Cotic, Jana de Villiers, Olubanké Dzahini, Frances Elmslie, Katie Evans, Shreyans Gandhi, Dyfrig A. Hughes, Huajie Jin, Daniele Panconesi, Anna Skowronska, Sanjay M. Sisodiya, Ed Silva, Vicky Stinton, Sara Stuart‐Smith, Sarah Tarrant, David Taylor, Lauren Varney, James T. R. Walters, Michelle Wood, Jessica Woodley, Cinzia Dello Russo, Munir Pirmohamed, Elvira Bramon   +29 more
wiley   +1 more source

To the Iranian Etymology of the Ethnonyms Mari, Merya, Muroma

Вопросы ономастики
The article continues the exploration of the ethnonym *märə, previously reconstructed by the author and A. V. Savelyev, as evidenced in the self-designation of the Mari people and in the names of Merya and Muroma found in Russian chronicles.
Vladimir V. Napolskikh
doaj   +1 more source

Teacher‐makers and teacher‐breakers: (Re)defining how status and safety influence trajectories into and away from teaching

British Educational Research Journal, EarlyView.
Abstract This paper uses empirical data from a longitudinal qualitative study conducted with aspirant teachers in England to propose (re)definitions of the concepts of ‘status’ and ‘safety’ as a framework with which to understand and improve teacher recruitment.
Emily MacLeod
wiley   +1 more source

Learning to ‘be’ an activist: Exploring the relationship between activism and informal education in a youth activism group case study

British Educational Research Journal, EarlyView.
Abstract Young people in the United States (and beyond) access spaces for activism in varied ways, including the out‐of‐school time sector, where youth activism (YA) groups draw on informal learning pedagogies to engage young people in collective action.
Laura Weiner
wiley   +1 more source

Hong Kong's non‐local undergraduate recruitment: Policies, institutional practices and student perspectives

British Educational Research Journal, EarlyView.
Abstract Beneath the Hong Kong government's enthusiasm for recruiting non‐local undergraduates—including students from the Chinese Mainland and other international regions—lies a longstanding gap in understanding the core meanings and drivers shaping the territory's expanding focus on inward international student mobility (ISM).
Fang Gao, Wei Yan Xiong, Hei‐hang Hayes Tang, Xiao Han   +3 more
wiley   +1 more source