Results 211 to 220 of about 2,078,280 (306)
In advanced colorectal cancer, tumors with mature tertiary lymphoid structures (TLS) exhibited abundant infiltration of CD3‐ and CD8‐positive lymphocytes in both primary and metastatic sites, indicating an activated immune response. The presence of mature TLS was also associated with favorable chemotherapy sensitivity and improved prognosis.
Nobuhiro Hosoi +9 more
wiley +1 more source
Hearing Loss in Young and Middle-Aged Adults as a Modifiable Risk Factor for Late-Life Dementia: A Systematic Review and Meta-Analysis. [PDF]
Satheesan L +3 more
europepmc +1 more source
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki +9 more
wiley +1 more source
Quality of life in patients with chronic kidney disease in low- and middle-income countries: protocol for a systematic review and meta-analysis. [PDF]
Muxunov A +3 more
europepmc +1 more source
ABSTRACT Background Self‐expandable metal stents (SEMS) are often used for preoperative biliary drainage in pancreatoduodenectomy (PD); however, their impact on postoperative intra‐abdominal infection (POAI) remains unclear. This study aimed to evaluate the clinical significance of SEMS in relation to POAI.
Kosuke Mori +9 more
wiley +1 more source
Low-research settings: is there a need for specific attention from funders? [PDF]
de Silva S, English M, Newton P.
europepmc +1 more source
This retrospective study identified low preoperative psoas muscle volume, measured by computed tomography, as an independent predictor of postoperative complications in patients undergoing emergency surgery for strangulated small bowel obstruction. Low psoas muscle volume, particularly in older adults, was associated with cardiopulmonary and systemic ...
Takuya Shiraishi +9 more
wiley +1 more source
Experiences and Perspectives of Caregivers of Francophone Older Adults Accessing Community Health Services in Toronto: an Exploratory Qualitative Study. [PDF]
Boyd EK +4 more
europepmc +1 more source
This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima +3 more
wiley +1 more source

