Results 221 to 230 of about 1,213,197 (307)
Challenges and Future Directions in Assessing the Quality and Completeness of Advanced Materials Safety Data for Re‐Usability: A Position Paper From the Nanosafety Community
Advanced Sustainable Systems, EarlyView.Nanosafety data provide a guiding example for establishing best practices in data management, aligning with FAIR principles and quality criteria. This review explores existing quality assessment approaches for reliability, relevance, and completeness, emphasizing the need for harmonization and adaptation to nanomaterials and advanced materials. The aim Verónica I. Dumit, Irini Furxhi, Penny Nymark, Antreas Afantitis, Ammar Ammar, Monica J. B. Amorim, Dalila Antunes, Svetlana Avramova, Chiara L. Battistelli, Gianpietro Basei, Cecilia Bossa, Emil Cimpan, Mihaela Roxana Cimpan, Dmitri Ciornii, Anna Costa, Camilla Delpivo, Maria Dusinska, Ana Sofia Fonseca, Steffi Friedrichs, Vasile‐Dan Hodoroaba, Danail Hristozov, Panagiotis Isigonis, Nina Jeliazkova, Nikolay Kochev, Eva Kranjc, Dieter Maier, Georgia Melagraki, Anastasios G. Papadiamantis, Tomasz Puzyn, Hubert Rauscher, Katie Reilly, Araceli Sánchez Jiménez, Janeck J. Scott‐Fordsmand, Neeraj Shandilya, Hyun Kil Shin, Gergana Tancheva, Jeaphianne P. M. van Rijn, Egon L. Willighagen, Ewelina Wyrzykowska, Martine I. Bakker, Damjana Drobne, Thomas E. Exner, Martin Himly, Iseult Lynch +43 morewiley +1 more sourceIndocyanine green lymphography imaging of normal lymphatic drainage in the lower limbs. [PDF]
Br J RadiolMills M, van Zanten M, Brezgyte G, Ho B, Pearce J, Wilken-Smith S, Shelton M, Mortimer P, Suami H, Gordon K, Ostergaard P. +10 moreeuropepmc +1 more sourceBacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage
Advanced Science, EarlyView.The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu +10 morewiley +1 more sourceLiver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Advanced Science, EarlyView.Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo +9 morewiley +1 more sourceMachine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles
Advanced Science, EarlyView.Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.Kaixiang Zhuang, Ji Chen, Jinfeng Han, Wei Cheng, Jiang Qiu, Jianfeng Feng, Simon Eickhoff, Deniz Vatansever +7 morewiley +1 more sourceSelf-Supervised Text-Vision Alignment for Automated Brain MRI Abnormality Detection: A Multicenter Study (ALIGN Study). [PDF]
Radiol Artif IntellWood DA, Guilhem E, Kafiabadi S, Al Busaidi A, Dissanayake K, Hammam A, Mansoor N, Townend M, Agarwal S, Wei Y, Mazumder A, Barker GJ, Sasieni P, Ourselin S, Cole JH, Nair N, Geetha A, Onyekwuluje C, Dineen R, Dhillon P, Costigan C, Fatania K, Igra M, Nichols R, Saada J, Juette A, Barbara RR, Spohr H, Booth TC, MIDI Consortium Group. +29 moreeuropepmc +1 more sourceSingle‐Cell RNA Sequencing of Human Lung Tissues Reveals Metallothionein‐Positive T Cells as a Novel Potential Marker of Susceptibility to Chronic Obstructive Pulmonary Disease
Advanced Science, EarlyView.Using single‐cell RNA sequencing of lung samples and flow cytometry of peripheral blood, we identified a novel T cell subset with high metallothionein (MT) expression. These MT‐high T cells suppress CD8+ T cell cytotoxicity and are progressively depleted from healthy controls to chronic obstructive pulmonary disease (COPD) patients, positioning them as Zengqing Liu, Xiaoxia Ren, Mi Mu, Huanyu Long, Jialu Lv, Zhihong Feng, Jie Liu, Jiajia Wang, Hui Deng, Fanyu Shi, Muzhi Zhang, Ruoyang Zhang, Yang Liu, Mengyu Xu, Yang Fan, Zengtao Wang, Zhe Lv, Yan Chen, Chris J. Corrigan, Ying Sun, Yahong Chen, Chen Chen, Ye Cui, Wei Wang +23 morewiley +1 more source